Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C22H35NO2.ClH |
| Molecular Weight | 381.98 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CCN(CCCC(=O)C1CCCCC1)C(C)CC2=CC=C(OC)C=C2
InChI
InChIKey=YBNFCHDBXWWVCU-UHFFFAOYSA-N
InChI=1S/C22H35NO2.ClH/c1-4-23(16-8-11-22(24)20-9-6-5-7-10-20)18(2)17-19-12-14-21(25-3)15-13-19;/h12-15,18,20H,4-11,16-17H2,1-3H3;1H
| Molecular Formula | C22H35NO2 |
| Molecular Weight | 345.5188 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Secoverine is a selective muscarinic receptor antagonist that was studied as a neurotropic spasmolytic agent. It was shown that the drug had no nicotinolytic or antihistaminic activity, a moderate antisterotonic activity, an inhibiting effect on the noradrenaline uptake mechanism of the vas deferens and marked local anesthetic activity.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pharmacology of secoverine, a new spasmolytic agent with specific antimuscarinic properties. Part 1: Antimuscarinic and spasmolytic effects. | 1980 |
|
| Comparison of the affinity of secoverine for some muscarinic receptors. | 1985 Jan-Feb |
|
| Secoverine is a non-selective muscarinic antagonist on rat heart and brain receptors. | 1986 Aug 7 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:14:34 GMT 2023
by
admin
on
Fri Dec 15 15:14:34 GMT 2023
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| Record UNII |
0R7XZP87ZX
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| Record Status |
Validated (UNII)
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| Record Version |
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29698
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NCI_THESAURUS |
C29704
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| Code System | Code | Type | Description | ||
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0R7XZP87ZX
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C028187
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42471
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C97982
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57558-46-0
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DTXSID90973133
Created by
admin on Fri Dec 15 15:14:34 GMT 2023 , Edited by admin on Fri Dec 15 15:14:34 GMT 2023
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PRIMARY |
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PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |