SECOVERINE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C22H35NO2.ClH
Molecular Weight	381.98
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCN(CCCC(=O)C1CCCCC1)C(C)CC2=CC=C(OC)C=C2

InChI

InChIKey=YBNFCHDBXWWVCU-UHFFFAOYSA-N

InChI=1S/C22H35NO2.ClH/c1-4-23(16-8-11-22(24)20-9-6-5-7-10-20)18(2)17-19-12-14-21(25-3)15-13-19;/h12-15,18,20H,4-11,16-17H2,1-3H3;1H

HIDE SMILES / InChI

Molecular Formula	C22H35NO2
Molecular Weight	345.5188
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3758175 | https://www.ncbi.nlm.nih.gov/pubmed/7193020

Secoverine is a selective muscarinic receptor antagonist that was studied as a neurotropic spasmolytic agent. It was shown that the drug had no nicotinolytic or antihistaminic activity, a moderate antisterotonic activity, an inhibiting effect on the noradrenaline uptake mechanism of the vas deferens and marked local anesthetic activity.

Approval Year

PubMed

Title	Date	PubMed
Secoverine is a non-selective muscarinic antagonist on rat heart and brain receptors.	1986-08-07	3758175
Comparison of the affinity of secoverine for some muscarinic receptors.	1985-01-01	4006314
Pharmacology of secoverine, a new spasmolytic agent with specific antimuscarinic properties. Part 1: Antimuscarinic and spasmolytic effects.	1980	7193020

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:51:24 GMT 2025` Edited by `admin` on `Mon Mar 31 17:51:24 GMT 2025`
Record UNII	0R7XZP87ZX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SECOVERINE HYDROCHLORIDE

Common Name

English

1-BUTANONE, 1-CYCLOHEXYL-4-(N-ETHYL(P-METHOXY-.ALPHA.-METHYLPHENETHYL)AMINO)-, HYDROCHLORIDE

Preferred Name

English

SECOVERINE HCL

Common Name

English

1-CYCLOHEXYL-4-((ETHYL-P-METHOXY-.ALPHA.-METHYLPHENETHYL)AMINO)-1-BUTANONE HYDROCHLORIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29698