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Details

Stereochemistry ACHIRAL
Molecular Formula 2Fe.3O4S
Molecular Weight 399.878
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERRIC SULFATE ANHYDROUS

SMILES

[Fe+3].[Fe+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O

InChI

InChIKey=RUTXIHLAWFEWGM-UHFFFAOYSA-H
InChI=1S/2Fe.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6

HIDE SMILES / InChI

Molecular Formula O4S
Molecular Weight 96.063
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Ferric chloride is a compound used as a food additive, a haemostatic or treatment for hypochromic anaemia. Ferric chloride induced vascular injury is a widely used model of occlusive thrombosis that reports platelet activation and aggregation in the context of an aseptic closed vascular system. Iron i.v. ferric chloride (960 mg) has being shown to be effective in correcting anaemia in HD patients with iron deficiency.

Originator

Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Additrace N

Approved Use

A source of electrolytes and trace elements as an integral part of a complete intravenous nutritional regimen, for adults and children over 40 kg.
Preventing
Parmirin

Approved Use

Preventive treatment of iron deficiency
Primary
Unknown

Approved Use

Unknown
Primary
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

1998
Curative
RADIOGARDASE

Approved Use

Insoluble Prussian blue is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination.

Launch Date

2003
Palliative
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

2014
PubMed

PubMed

TitleDatePubMed
Carcinogenicity studies on natural and man-made fibres with the intraperitoneal test in rats.
1989
Effect of physical exercise and vitamin C on absorption of ferric sodium citrate.
1996 Dec
Metal-mediated cyclization of aryl and benzyl glycidyl ethers: a complete scenario.
2008 Dec 17
Heme Binding by Corynebacterium diphtheriae HmuT: Function and Heme Environment.
2015 Nov 3
Nazarov cyclization of 1,4-pentadien-3-ols: preparation of cyclopenta[b]indoles and spiro[indene-1,4'-quinoline]s.
2016 Feb 14
Mechanisms and origins of the switchable regioselectivity of FeBr3-catalyzed [1,2]-aryl and [1,2]-alkyl shifts of α-aryl aldehydes.
2016 Feb 28
Ferric Chloride-induced Murine Thrombosis Models.
2016 Sep 5
Phosphorus recovery from biogas slurry by ultrasound/H(2)O(2) digestion coupled with HFO/biochar adsorption process.
2017 Feb
Effect of iron and carbon monoxide on fibrinogenase-like degradation of plasmatic coagulation by venoms of four Crotalus species.
2017 Jan
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
Ferric sodium citrate is an additive used in various foods such as baby milk powder, school and hospital food, beverages, cereals and supplements. It is administered orally.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 02:14:55 GMT 2023
Edited
by admin
on Sat Dec 16 02:14:55 GMT 2023
Record UNII
4YKQ1X5E5Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERRIC SULFATE ANHYDROUS
Common Name English
IRON SULFATE (FE2(SO4)3)
Common Name English
IRON SESQUISULFATE
Common Name English
FERRIC SULFATE [INCI]
Common Name English
FERRIC SULFATE [MI]
Common Name English
SULFURIC ACID, IRON(3+) SALT (3:2)
Common Name English
FERRIC PERSULFATE
Common Name English
IRON(III) SULFATE
Systematic Name English
Ferric sulfate [WHO-DD]
Common Name English
Code System Code Type Description
FDA UNII
4YKQ1X5E5Y
Created by admin on Sat Dec 16 02:14:55 GMT 2023 , Edited by admin on Sat Dec 16 02:14:55 GMT 2023
PRIMARY
CHEBI
53438
Created by admin on Sat Dec 16 02:14:55 GMT 2023 , Edited by admin on Sat Dec 16 02:14:55 GMT 2023
PRIMARY
CAS
10124-49-9
Created by admin on Sat Dec 16 02:14:55 GMT 2023 , Edited by admin on Sat Dec 16 02:14:55 GMT 2023
NON-SPECIFIC STOICHIOMETRY
MERCK INDEX
m5329
Created by admin on Sat Dec 16 02:14:55 GMT 2023 , Edited by admin on Sat Dec 16 02:14:55 GMT 2023
PRIMARY Merck Index
EPA CompTox
DTXSID5029712
Created by admin on Sat Dec 16 02:14:55 GMT 2023 , Edited by admin on Sat Dec 16 02:14:55 GMT 2023
PRIMARY
SMS_ID
100000087149
Created by admin on Sat Dec 16 02:14:55 GMT 2023 , Edited by admin on Sat Dec 16 02:14:55 GMT 2023
PRIMARY
WIKIPEDIA
IRON(III) SULFATE
Created by admin on Sat Dec 16 02:14:55 GMT 2023 , Edited by admin on Sat Dec 16 02:14:55 GMT 2023
PRIMARY
CAS
10028-22-5
Created by admin on Sat Dec 16 02:14:55 GMT 2023 , Edited by admin on Sat Dec 16 02:14:55 GMT 2023
PRIMARY
HSDB
6311
Created by admin on Sat Dec 16 02:14:55 GMT 2023 , Edited by admin on Sat Dec 16 02:14:55 GMT 2023
PRIMARY
PUBCHEM
24826
Created by admin on Sat Dec 16 02:14:55 GMT 2023 , Edited by admin on Sat Dec 16 02:14:55 GMT 2023
PRIMARY
ECHA (EC/EINECS)
233-072-9
Created by admin on Sat Dec 16 02:14:55 GMT 2023 , Edited by admin on Sat Dec 16 02:14:55 GMT 2023
PRIMARY
ECHA (EC/EINECS)
233-336-3
Created by admin on Sat Dec 16 02:14:55 GMT 2023 , Edited by admin on Sat Dec 16 02:14:55 GMT 2023
ALTERNATIVE
Related Record Type Details
SOLVATE->ANHYDROUS
Related Record Type Details
ACTIVE MOIETY