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ACAVAMERAN
4Y426OW1GF
Investigational
General
Record Details
Names
4
Identifiers
4
Subunits
1
Sugars
2
Linkages
1
Relationships
1
Active Moiety
1
Modifications
2
ACAVAMERAN
4Y426OW1GF
Investigational
General
Approval Year
Unknown
139,594
Record Details
Substance Class
Nucleic Acid
Nucleic Acid Type
MRNA
Nucleic Acid Subtype
Sequence Type
COMPLETE
Record UNII
4Y426OW1GF
Record Status
Validated (UNII)
Record Version
12
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2
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Names
4
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Name
Type
Language
Name
Type
Language
ACAVAMERAN
Official Name
English
MESSENGER RNA (MRNA), 5' CAPPED, ENCODING TUMOUR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 4 (TNFSF4, OX40 LIGAND, OX40L, GLYCOPROTEIN GP34), FLANKED BY 5' AND 3' UNTRANSLATED REGIONS AND A 3' POLYA TAIL; CONTAINS N1-METHYLPSEUDOURIDINE INSTEAD OF URIDIN
Common Name
English
RNA (ALL URIDINE->N1-METHYLPSEUDOURIDINE-SUBSTITUTED HUMAN GENE TNFSF4 CD252 ANTIGEN-SPECIFYING MESSENGER PLUS FLANKS)
Common Name
English
acavameran [INN]
Common Name
English
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Identifiers
4
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Code System
Code
Type
Description
Code System
Code
Type
Description
NCI_THESAURUS
C179068
PRIMARY
FDA UNII
4Y426OW1GF
PRIMARY
INN
11264
PRIMARY
INN
CAS
2159155-74-3
PRIMARY
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Subunits
1
Sugars
2
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Sugar
Site Range
Site Count
Sugar
Site Range
Site Count
2'-O-Methyl-Ribose
1_2
1 / 845
D-Ribose (RNA)
1_3-1_846
844 / 845
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Linkages
1
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Linkage
Site Range
Site Count
Linkage
Site Range
Site Count
Phosphate
1_2-1_846
845 / 844
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Relationships
1
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Related Record
Type
Details
Related Record
Type
Details
SD6YM06CAN
TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 4
EXPRESSED PROTEIN->VECTOR
Amount:
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1
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Related Record
Type
Details
Related Record
Type
Details
4Y426OW1GF
ACAVAMERAN
ACTIVE MOIETY
Comments:
OX40 ligand stimulants
Amount:
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Modifications
2
Structural Modifications
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Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
NUCLEOTIDE SUBSTITUTION
[1_1]
5'-TERMINUS
5'-GUANOSINE-M-RNA-CAP-1-3'-PHOSPHATE
T0HQY09X7B
NUCLEOSIDE_SUBSTITUTION
RESIDUE_SPECIFIC
U
6-METHYLPSEUDOURIDINE
2W14ED8VLI
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