SIB-1893

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H13N
Molecular Weight	195.2597
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of SIB-1893

Structure Search

SMILES

CC1=NC(\C=C\C2=CC=CC=C2)=CC=C1

InChI

InChIKey=SISOFUCTXZKSOQ-ZHACJKMWSA-N

InChI=1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+

HIDE SMILES / InChI

Molecular Formula	C14H13N
Molecular Weight	195.2597
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Metabotropic glutamate receptor 5 40 Target ID: CHEMBL3227 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10381773	Antagonist 2849		0.29 µM [IC50]

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:54:31 GMT 2025` Edited by `admin` on `Wed Apr 02 09:54:31 GMT 2025`
Record UNII	4X2F5X24UK
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NSC-36665

Preferred Name

English

SIB-1893

Code

English

PYRIDINE, 2-METHYL-6-((1E)-2-PHENYLETHENYL)-

Common Name

English

TRANS-6-STYRYL-2-PICOLINE

Common Name

English

Code System Code Type Description

FDA UNII

4X2F5X24UK

Created by admin on Wed Apr 02 09:54:31 GMT 2025 , Edited by admin on Wed Apr 02 09:54:31 GMT 2025

PRIMARY

EPA CompTox

DTXSID801017353

Created by admin on Wed Apr 02 09:54:31 GMT 2025 , Edited by admin on Wed Apr 02 09:54:31 GMT 2025

PRIMARY

NSC

36665

Created by admin on Wed Apr 02 09:54:31 GMT 2025 , Edited by admin on Wed Apr 02 09:54:31 GMT 2025

PRIMARY

PUBCHEM

5311432

Created by admin on Wed Apr 02 09:54:31 GMT 2025 , Edited by admin on Wed Apr 02 09:54:31 GMT 2025

PRIMARY

CAS

6266-99-5

Created by admin on Wed Apr 02 09:54:31 GMT 2025 , Edited by admin on Wed Apr 02 09:54:31 GMT 2025

NON-SPECIFIC STEREOCHEMISTRY

WIKIPEDIA

SIB-1893

Created by admin on Wed Apr 02 09:54:31 GMT 2025 , Edited by admin on Wed Apr 02 09:54:31 GMT 2025

PRIMARY

CAS

7370-21-0

Created by admin on Wed Apr 02 09:54:31 GMT 2025 , Edited by admin on Wed Apr 02 09:54:31 GMT 2025

PRIMARY

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METABOTROPIC GLUTAMATE RECEPTOR 5

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Interaction Type:

ANTAGONIST

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					YZN9W7P1BX

METABOTROPIC GLUTAMATE RECEPTOR 4

TARGET -> ACTIVATOR

Comments:

Positive allosteric modulator

Interaction Type:

ALLOSTERIC

Amount:

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					4X2F5X24UK

SIB-1893

ACTIVE MOIETY

Amount: