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Details

Stereochemistry ABSOLUTE
Molecular Formula 2C4H5NO4.Zn.2H
Molecular Weight 329.598
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ZINC ASPARTATE

SMILES

[H+].[H+].[Zn++].N[C@@H](CC([O-])=O)C([O-])=O.N[C@@H](CC([O-])=O)C([O-])=O

InChI

InChIKey=POEVDIARYKIEGF-CEOVSRFSSA-L
InChI=1S/2C4H7NO4.Zn/c2*5-2(4(8)9)1-3(6)7;/h2*2H,1,5H2,(H,6,7)(H,8,9);/q;;+2/p-2/t2*2-;/m00./s1

HIDE SMILES / InChI
Molecular Formula H
Molecular Weight 1.0079
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C4H5NO4
Molecular Weight 131.0868
Charge -2
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula Zn
Molecular Weight 65.409
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Zinc aspartate is an approved drug, used to treat zinc deficiency in humans. Zinc aspartate regulates the production of the growth hormone and sex hormones (it is necessary for the production of sperm cells and egg cells). It reduces the body’s susceptibility to infections and allergies. It promotes the proper secretion of insulin by the pancreas. Zinc deficiency causes: disorders in the functioning of the skin, the digestive system, the nervous system, the immunological system, and the skeletal system. Significant zinc deficiency can cause dwarfism and genital underdevelopment. Zinc aspartate suppresses experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS), as well as effector T cell functions in vitro.

Approval Year

2019
334
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Preclinical
Unknown

Approved Use

Unknown
Preventing
Preclinical
Unknown

Approved Use

Unknown
Primary
Preclinical
Unknown

Approved Use

Unknown
Primary
Approved
8429
Zincas

Approved Use

Indications for use: complementation of zinc deficiency in the body
Palliative
Preclinical
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Patents

Patents

US20020122835
1
US4622220
1

Sample Use Guides

In Vivo Use Guide
For inflammatory bowel disease, 300 milligrams of zinc aspartate (equal to 60 milligrams of elemental zinc) has been taken by mouth daily for four weeks.
Route of Administration: Oral
In Vitro Use Guide
Zinc aspartate, at a concentration of 16 uM, increased human fibroblasts proliferation in cell culture
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:02:12 GMT 2023
Edited
by admin
on Fri Dec 15 16:02:12 GMT 2023
Record UNII
4OC7QTI23H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ZINC ASPARTATE
INCI  
INCI  
Official Name English
Aspartate zinc [WHO-DD]
Common Name English
ZINCATE(2-), BIS(L-ASPARTATO(2-)-.KAPPA.N,.KAPPA.O1)-, HYDROGEN (1:2), (T-4)-
Common Name English
ZINC ASPARTATE [INCI]
Common Name English
ZINCATE(2-), BIS(L-ASPARTATO(2-)-N,O(SUP 1))-, DIHYDROGEN, (T-4)-
Common Name English
ASPARTATE ZINC
WHO-DD  
Systematic Name English
DIHYDROGEN BIS(L-ASPARTATO(2-)-N,O1)ZINCATE(2-)
Common Name English
Classification Tree Code System Code
DSLD 137 (Number of products:9660)
Created by admin on Fri Dec 15 16:02:12 GMT 2023 , Edited by admin on Fri Dec 15 16:02:12 GMT 2023
Code System Code Type Description
EVMPD
SUB12952MIG
Created by admin on Fri Dec 15 16:02:12 GMT 2023 , Edited by admin on Fri Dec 15 16:02:12 GMT 2023
PRIMARY
FDA UNII
4OC7QTI23H
Created by admin on Fri Dec 15 16:02:12 GMT 2023 , Edited by admin on Fri Dec 15 16:02:12 GMT 2023
PRIMARY
RXCUI
236142
Created by admin on Fri Dec 15 16:02:12 GMT 2023 , Edited by admin on Fri Dec 15 16:02:12 GMT 2023
PRIMARY RxNorm
DAILYMED
4OC7QTI23H
Created by admin on Fri Dec 15 16:02:12 GMT 2023 , Edited by admin on Fri Dec 15 16:02:12 GMT 2023
PRIMARY
NCI_THESAURUS
C87349
Created by admin on Fri Dec 15 16:02:12 GMT 2023 , Edited by admin on Fri Dec 15 16:02:12 GMT 2023
PRIMARY
PUBCHEM
56841018
Created by admin on Fri Dec 15 16:02:12 GMT 2023 , Edited by admin on Fri Dec 15 16:02:12 GMT 2023
PRIMARY
ECHA (EC/EINECS)
253-012-5
Created by admin on Fri Dec 15 16:02:12 GMT 2023 , Edited by admin on Fri Dec 15 16:02:12 GMT 2023
PRIMARY
WIKIPEDIA
Zinc aspartate
Created by admin on Fri Dec 15 16:02:12 GMT 2023 , Edited by admin on Fri Dec 15 16:02:12 GMT 2023
PRIMARY
CAS
36393-20-1
Created by admin on Fri Dec 15 16:02:12 GMT 2023 , Edited by admin on Fri Dec 15 16:02:12 GMT 2023
PRIMARY
NCI_THESAURUS
C1505
Created by admin on Fri Dec 15 16:02:12 GMT 2023 , Edited by admin on Fri Dec 15 16:02:12 GMT 2023
CONCEPT Dietary Supplement
SMS_ID
100000089091
Created by admin on Fri Dec 15 16:02:12 GMT 2023 , Edited by admin on Fri Dec 15 16:02:12 GMT 2023
PRIMARY
Related Record Type Details
Structure of ZINC CATION
PARENT -> SALT/SOLVATE
Structure of ASPARTIC ACID
PARENT -> SALT/SOLVATE
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