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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H20F4N6O2
Molecular Weight 440.3947
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GDC-0134

SMILES

NC1=NC=C(C=C1OC(F)F)C2=CC(=NC(=N2)N3CCC(F)(F)C3)N4C[C@@H]5C[C@H]4CO5

InChI

InChIKey=SKMKJBYBPYBDMN-RYUDHWBXSA-N
InChI=1S/C19H20F4N6O2/c20-17(21)31-14-3-10(6-25-16(14)24)13-5-15(29-7-12-4-11(29)8-30-12)27-18(26-13)28-2-1-19(22,23)9-28/h3,5-6,11-12,17H,1-2,4,7-9H2,(H2,24,25)/t11-,12-/m0/s1

HIDE SMILES / InChI

Molecular Formula C19H20F4N6O2
Molecular Weight 440.3947
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 10:16:14 GMT 2023
Edited
by admin
on Sat Dec 16 10:16:14 GMT 2023
Record UNII
4N6KQ7D685
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GDC-0134
Common Name English
RG-6000
Common Name English
2-PYRIDINAMINE, 3-(DIFLUOROMETHOXY)-5-(2-(3,3-DIFLUORO-1-PYRROLIDINYL)-6-(1S,4S)-2-OXA-5-AZABICYCLO(2.2.1)HEPT-5-YL-4-PYRIMIDINYL)-
Systematic Name English
Code System Code Type Description
FDA UNII
4N6KQ7D685
Created by admin on Sat Dec 16 10:16:14 GMT 2023 , Edited by admin on Sat Dec 16 10:16:14 GMT 2023
PRIMARY
CAS
1637394-01-4
Created by admin on Sat Dec 16 10:16:14 GMT 2023 , Edited by admin on Sat Dec 16 10:16:14 GMT 2023
PRIMARY
PUBCHEM
86298636
Created by admin on Sat Dec 16 10:16:14 GMT 2023 , Edited by admin on Sat Dec 16 10:16:14 GMT 2023
PRIMARY
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
BRAIN/PLASMA RATIO BIOLOGICAL