GDC-0134

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H20F4N6O2
Molecular Weight	440.3947
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=NC=C(C=C1OC(F)F)C2=CC(=NC(=N2)N3CCC(F)(F)C3)N4C[C@@H]5C[C@H]4CO5

InChI

InChIKey=SKMKJBYBPYBDMN-RYUDHWBXSA-N

InChI=1S/C19H20F4N6O2/c20-17(21)31-14-3-10(6-25-16(14)24)13-5-15(29-7-12-4-11(29)8-30-12)27-18(26-13)28-2-1-19(22,23)9-28/h3,5-6,11-12,17H,1-2,4,7-9H2,(H2,24,25)/t11-,12-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C19H20F4N6O2
Molecular Weight	440.3947
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:16:14 GMT 2023` Edited by `admin` on `Sat Dec 16 10:16:14 GMT 2023`
Record UNII	4N6KQ7D685
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GDC-0134

Common Name

English

RG-6000

Common Name

English

2-PYRIDINAMINE, 3-(DIFLUOROMETHOXY)-5-(2-(3,3-DIFLUORO-1-PYRROLIDINYL)-6-(1S,4S)-2-OXA-5-AZABICYCLO(2.2.1)HEPT-5-YL-4-PYRIMIDINYL)-

Systematic Name

English

Code System Code Type Description

FDA UNII

4N6KQ7D685

Created by admin on Sat Dec 16 10:16:14 GMT 2023 , Edited by admin on Sat Dec 16 10:16:14 GMT 2023

PRIMARY

CAS

1637394-01-4

Created by admin on Sat Dec 16 10:16:14 GMT 2023 , Edited by admin on Sat Dec 16 10:16:14 GMT 2023

PRIMARY

PUBCHEM

86298636

Created by admin on Sat Dec 16 10:16:14 GMT 2023 , Edited by admin on Sat Dec 16 10:16:14 GMT 2023

PRIMARY

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MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 12

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					4N6KQ7D685

GDC-0134

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
BRAIN/PLASMA RATIO	BIOLOGICAL