U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:30:03 GMT 2023
Edited
by admin
on Sat Dec 16 14:30:03 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED
Sequence Type COMPLETE
Record UNII
4I9I5X3Z6N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VUDALIMAB
USAN   INN  
Official Name English
IMMUNOGLOBULIN HALF-IG G1-KAPPA/SCFV-H-CH2-CH3, ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)) AND ANTI-(HOMO SAPIENSPDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), MONOCLONAL ANTIBODY, BISPECIFIC
Common Name English
Vudalimab [WHO-DD]
Common Name English
PD-1 X CTLA-4 DUAL CHECKPOINT INHIBITOR XMAB20717
Common Name English
IMMUNOGLOBULIN, ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4) (HUMAN-MUS MUSCULUS MONOCLONAL XMAB20717 SINGLE-CHAIN VARIABLE FRAGMENT VL-LINKER-VH) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN .GAMMA.1-CHAIN C-REGION C-TERMINAL FRAGMENT), (260
Common Name English
ANTI-PD-1/ANTI-CTLA-4 XMAB20717
Common Name English
XMAB20717
Code English
VUDALIMAB [USAN]
Common Name English
vudalimab [INN]
Common Name English
ANTI-PD1/CTLA4 BISPECIFIC ANTIBODY XMAB20717
Common Name English
XMAB-20717
Common Name English
Code System Code Type Description
NCI_THESAURUS
C150463
Created by admin on Sat Dec 16 14:30:03 GMT 2023 , Edited by admin on Sat Dec 16 14:30:03 GMT 2023
PRIMARY
FDA UNII
4I9I5X3Z6N
Created by admin on Sat Dec 16 14:30:03 GMT 2023 , Edited by admin on Sat Dec 16 14:30:03 GMT 2023
PRIMARY
CAS
2329669-72-7
Created by admin on Sat Dec 16 14:30:03 GMT 2023 , Edited by admin on Sat Dec 16 14:30:03 GMT 2023
PRIMARY
CAS
2303884-42-4
Created by admin on Sat Dec 16 14:30:03 GMT 2023 , Edited by admin on Sat Dec 16 14:30:03 GMT 2023
NO STRUCTURE GIVEN
USAN
JK-26
Created by admin on Sat Dec 16 14:30:03 GMT 2023 , Edited by admin on Sat Dec 16 14:30:03 GMT 2023
PRIMARY
INN
11464
Created by admin on Sat Dec 16 14:30:03 GMT 2023 , Edited by admin on Sat Dec 16 14:30:03 GMT 2023
PRIMARY
From To
1_22 1_96
1_145 1_201
1_221 3_215
1_227 2_260
1_230 2_263
1_261 1_321
1_367 1_425
2_23 2_88
2_149 2_225
2_294 2_354
2_400 2_458
3_23 3_89
3_135 3_195
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_330
Related Record Type Details
TARGET -> INHIBITOR
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL