Details
Stereochemistry | ACHIRAL |
Molecular Formula | C17H12O8 |
Molecular Weight | 344.2724 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCC1=C2OC(=CC(=O)C2=CC3=C1OC(=CC3=O)C(O)=O)C(O)=O
InChI
InChIKey=WEQNUNAIQXHGHB-UHFFFAOYSA-N
InChI=1S/C17H12O8/c1-2-3-7-14-8(10(18)5-12(24-14)16(20)21)4-9-11(19)6-13(17(22)23)25-15(7)9/h4-6H,2-3H2,1H3,(H,20,21)(H,22,23)
Molecular Formula | C17H12O8 |
Molecular Weight | 344.2724 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Probicromil is a Histamine H1 antagonist. It was taken to the clinic and found to be effective in exercise and antigen challenge. Probicromil inhibited Ascaris-induced bronchoconstriction and the increase in plasma histamine levels seen after Ascaris inhalation. Therapeutic efficacy in seasonal rhinitis was also demonstrated. Further clinical studies were halted because of a side-effect associated with the compound, namely a sensation of warmth (especially in the perineal region) experienced by some volunteers after inhalation.
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:03:35 GMT 2023
by
admin
on
Fri Dec 15 16:03:35 GMT 2023
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Record UNII |
49BO3YUP40
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Record Status |
Validated (UNII)
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Record Version |
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-
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29714
Created by
admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
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Code System | Code | Type | Description | ||
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CHEMBL2110970
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58805-38-2
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admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
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C84108
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admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
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49BO3YUP40
Created by
admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
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100000087667
Created by
admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
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5098
Created by
admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
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C040112
Created by
admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
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71950
Created by
admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
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DTXSID10866710
Created by
admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
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SUB05396MIG
Created by
admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |
Related Record | Type | Details | ||
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ACTIVE MOIETY |