Details
Stereochemistry | ACHIRAL |
Molecular Formula | C17H10O8.Ca |
Molecular Weight | 382.335 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Ca++].CCCC1=C2OC(=CC(=O)C2=CC3=C1OC(=CC3=O)C([O-])=O)C([O-])=O
InChI
InChIKey=BTHYDDWGEVSYPS-UHFFFAOYSA-L
InChI=1S/C17H12O8.Ca/c1-2-3-7-14-8(10(18)5-12(24-14)16(20)21)4-9-11(19)6-13(17(22)23)25-15(7)9;/h4-6H,2-3H2,1H3,(H,20,21)(H,22,23);/q;+2/p-2
Molecular Formula | C17H10O8 |
Molecular Weight | 342.2565 |
Charge | -2 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | Ca |
Molecular Weight | 40.078 |
Charge | 2 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Probicromil is a Histamine H1 antagonist. It was taken to the clinic and found to be effective in exercise and antigen challenge. Probicromil inhibited Ascaris-induced bronchoconstriction and the increase in plasma histamine levels seen after Ascaris inhalation. Therapeutic efficacy in seasonal rhinitis was also demonstrated. Further clinical studies were halted because of a side-effect associated with the compound, namely a sensation of warmth (especially in the perineal region) experienced by some volunteers after inhalation.
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:08:15 GMT 2023
by
admin
on
Fri Dec 15 16:08:15 GMT 2023
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Record UNII |
0U434950BU
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Record Status |
Validated (UNII)
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Record Version |
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-
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Code | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Systematic Name | English |
Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29714
Created by
admin on Fri Dec 15 16:08:15 GMT 2023 , Edited by admin on Fri Dec 15 16:08:15 GMT 2023
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71144-97-3
Created by
admin on Fri Dec 15 16:08:15 GMT 2023 , Edited by admin on Fri Dec 15 16:08:15 GMT 2023
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C66469
Created by
admin on Fri Dec 15 16:08:15 GMT 2023 , Edited by admin on Fri Dec 15 16:08:15 GMT 2023
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22287988
Created by
admin on Fri Dec 15 16:08:15 GMT 2023 , Edited by admin on Fri Dec 15 16:08:15 GMT 2023
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0U434950BU
Created by
admin on Fri Dec 15 16:08:15 GMT 2023 , Edited by admin on Fri Dec 15 16:08:15 GMT 2023
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DTXSID40221338
Created by
admin on Fri Dec 15 16:08:15 GMT 2023 , Edited by admin on Fri Dec 15 16:08:15 GMT 2023
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CHEMBL2110970
Created by
admin on Fri Dec 15 16:08:15 GMT 2023 , Edited by admin on Fri Dec 15 16:08:15 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
Related Record | Type | Details | ||
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ACTIVE MOIETY |