U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C8H12N4O5
Molecular Weight 244.2047
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RIBAVIRIN

SMILES

NC(=O)C1=NN(C=N1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O

InChI

InChIKey=IWUCXVSUMQZMFG-AFCXAGJDSA-N
InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1

HIDE SMILES / InChI

Molecular Formula C8H12N4O5
Molecular Weight 244.2047
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Tue Mar 06 10:58:42 UTC 2018
Edited
by admin
on Tue Mar 06 10:58:42 UTC 2018
Record UNII
49717AWG6K
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RIBAVIRIN
EMA EPAR   EP   HSDB   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
USAN   INN  
Official Name English
COPEGUS
Brand Name English
COTRONAK
Brand Name English
RBV
Common Name English
RIBAVIRIN [INN]
Common Name English
1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE, 1-.BETA.-D-RIBOFURANOSYL-
Common Name English
RIBAVIRIN [HSDB]
Common Name English
RIBAVIRIN [EMA EPAR]
Common Name English
SCH 18908
Code English
SCH-18908
Code English
NSC-163039
Code English
RIBAVIRIN BIOPARTNERS
Brand Name English
RIBAVIRIN [MI]
Common Name English
RIBAVIRIN TEVA PHARMA B.V.
Brand Name English
REBETOL
Brand Name English
RIBAVIRIN MYLAN
Brand Name English
RIBAVIRIN [VANDF]
Common Name English
RIBAVIRIN [JAN]
Common Name English
RIBAVIRIN [MART.]
Common Name English
RIBAVIRIN [USP]
Common Name English
RIBAVIRIN [ORANGE BOOK]
Common Name English
RIBAVIRIN COMPONENT OF PEGINTERFERON
Common Name English
VIRAZOLE
Brand Name English
RIBASPHERE
Brand Name English
RIBAVIRIN [WHO-DD]
Common Name English
RIBAVIRIN [USAN]
Common Name English
RIBAVIRIN [EP]
Common Name English
RIBAVIRIN TEVA
Brand Name English
1-.BETA.-D-RIBOFURANOSYL-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
Common Name English
RIBAVIRIN [USP-RS]
Common Name English
Classification Tree Code System Code
NDF-RT N0000175466
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
EMA ASSESSMENT REPORTS RIBAVIRIN TEVA (AUTHORIZED: HEPATITIS C, CHRONIC)
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
EMA ASSESSMENT REPORTS RIBAVIRIN TEVA PHARMA B.V. (AUTHORIZED: HEPATITIS C, CHRONIC)
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
LIVERTOX 842
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
WHO-VATC QJ05AB04
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
EMA ASSESSMENT REPORTS COTRONAK (REFUSED: HEPATITIS C, CHRONIC)
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
NDF-RT N0000175459
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
WHO-ESSENTIAL MEDICINES LIST 6.4.3
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
EMA ASSESSMENT REPORTS REBETOL (AUTHORIZED: HEPATITIS C, CHRONIC)
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
WHO-ATC J05AB04
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
NDF-RT N0000175459
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
NDF-RT N0000175459
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
EMA ASSESSMENT REPORTS RIBAVIRIN BIOPARTNERS (WITHDRAWN: HEPATITIS C, CHRONIC)
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
EMA ASSESSMENT REPORTS RIBAVIRIN MYLAN (AUTHORIZED: HEPATITIS C, CHRONIC)
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
Code System Code Type Description
NCI_THESAURUS
C807
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY
INN
3543
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY
ChEMBL
CHEMBL1643
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY
MESH
D012254
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY
CAS
36791-04-5
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY
EVMPD
SUB10297MIG
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY
JAPANESE REVIEW
COPEGUS
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY APPROVED MARCH 2015
MERCK INDEX
M9593
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY Merck Index
EPA CompTox
36791-04-5
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY
LactMed
36791-04-5
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY
DRUG BANK
DB00811
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY
HSDB
36791-04-5
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY
IUPHAR
6842
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY
RXCUI
9344
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY RxNorm
WIKIPEDIA
RIBAVIRIN
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY
PUBCHEM
37542
Created by admin on Tue Mar 06 10:58:42 UTC 2018 , Edited by admin on Tue Mar 06 10:58:42 UTC 2018
PRIMARY SWITZERF
Related Record Type Details
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Related Record Type Details
METABOLITE -> PARENT
a degradative pathway involving deribosylation and amide hydrolysis to yield a triazole carboxylic acid metabolite; Excreted renally
METABOLITE -> PARENT
BY adenosine kinase
METABOLITE -> PARENT
a degradative pathway involving deribosylation and amide hydrolysis to yield a triazole carboxylic acid metabolite; excreted renally.
PRODRUG -> METABOLITE ACTIVE
Related Record Type Details
IMPURITY -> PARENT
UNSPECIFIED
EP
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 2.3
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
UNSPECIFIED
EP
IMPURITY -> PARENT
UNSPECIFIED
EP
IMPURITY -> PARENT
UNSPECIFIED
EP
IMPURITY -> PARENT
UNSPECIFIED
EP
Related Record Type Details
ACTIVE MOIETY