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Details

Stereochemistry ACHIRAL
Molecular Formula C15H13Cl2N5
Molecular Weight 334.203
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of ROBENIDINE

SMILES

ClC1=CC=C(C=C1)\C=N\NC(=N)N\N=C\C2=CC=C(Cl)C=C2

InChI

InChIKey=MOOFYEJFXBSZGE-LQGKIZFRSA-N
InChI=1S/C15H13Cl2N5/c16-13-5-1-11(2-6-13)9-19-21-15(18)22-20-10-12-3-7-14(17)8-4-12/h1-10H,(H3,18,21,22)/b19-9+,20-10+

HIDE SMILES / InChI

Molecular Formula C15H13Cl2N5
Molecular Weight 334.203
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 2
Optical Activity NONE

Description

Robenidine (l,3-6ts (p-chlorobenzylidenamino) guanidine hydrochloride) is an effective anticoccidial, first introduced by Kantor, Kennett, Waletzky & Tomcufcik (1970). It does not affect the earliest stages in the coccidial life-cycle and its main activity is against the almost mature first generation schizont. It is used as an aid in the prevention of coccidiosis caused by Eimeria mivati, E. brunetti, E. tenella, E. acervulina, E. maxima and E. necatrix in broiler chickens.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Robenz

PubMed

Sample Use Guides

In Vivo Use Guide
Chickens: Mix 1 pound of Robenz® (Robenidine Hydrochloride) Type A Medicated Article in one ton of feed to provide 30 grams per ton (0.0033%) robenidine hydrochloride concentration in feed. Feed continuously as the sole ration.
Route of Administration: Oral
In Vitro Use Guide
Robenidine was active against MRSA and VRE with MIC's of 8.1 and 4.7 uM, respectively.
Substance Class Chemical
Record UNII
4888ME6C4E
Record Status Validated (UNII)
Record Version