Bavebegene Tovacivec

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 20:09:00 GMT 2025` Edited by `admin` on `Wed Apr 02 20:09:00 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family	Poxviridae
Organism Genus	Orthopoxvirus
Organism Species	vaccinia virus
Infraspecific Type	RECOMBINANT VECTOR
Infraspecific Name	bavebegene tovacivec (MVA-HBV antigen)
Part	whole
Record UNII	47R2ZYV242
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DNA (recombinant modified Vaccinia virus Ankara-derived vaccine vector MVA-HBV endogenous F11 promoter plus hepatitis B virus C-terminal fragment of pre-S1 protein fused with pre-S2 protein fused with non-functional polymerase fused with pre-C protein fu

Preferred Name

English

Bavebegene Tovacivec

Common Name

English

bavebegene tovacivec [INN]

Common Name

English

recombinant non-replicating vaccinia virus (Modified Vaccinia Ankara strain [MVA]) encoding two codon-optimised fusion proteins adjacent to one another containing hepatitis B virus (HBV) antigens, with the first one comprising the C-terminal region of th

Common Name

English

Code System Code Type Description

CAS

2857059-65-3

Created by admin on Wed Apr 02 20:09:00 GMT 2025 , Edited by admin on Wed Apr 02 20:09:00 GMT 2025

PRIMARY

NCI_THESAURUS

C211731

Created by admin on Wed Apr 02 20:09:00 GMT 2025 , Edited by admin on Wed Apr 02 20:09:00 GMT 2025

PRIMARY

INN

12932

Created by admin on Wed Apr 02 20:09:00 GMT 2025 , Edited by admin on Wed Apr 02 20:09:00 GMT 2025

PRIMARY

FDA UNII

47R2ZYV242

Created by admin on Wed Apr 02 20:09:00 GMT 2025 , Edited by admin on Wed Apr 02 20:09:00 GMT 2025

PRIMARY

Related Record Type Details


					77H9EM77P7

HEPATITIS B VIRUS

TARGET ORGANISM->VACCINE ANTIGEN

Amount:

Related Record Type Details


					47R2ZYV242

Bavebegene Tovacivec

ACTIVE MOIETY

Comments:

gene therapy (immune response inducer, hepatitis B)

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
Whole genome with all the modifications					Bavebegene tovacivec whole genome	R8K5XU7LJQ