PAREPTIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

First approved in 2022

Possibly Marketed Outside US

First approved in 2022

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C14H26N4O3
Molecular Weight	298.3812
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PAREPTIDE

Structure Search

SMILES

CC(C)C[C@@H](N(C)C(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O

InChI

InChIKey=BXCQMQVEMFYKJC-WDEREUQCSA-N

InChI=1S/C14H26N4O3/c1-9(2)7-11(13(20)17-8-12(15)19)18(3)14(21)10-5-4-6-16-10/h9-11,16H,4-8H2,1-3H3,(H2,15,19)(H,17,20)/t10-,11+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C14H26N4O3
Molecular Weight	298.3812
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: Elks J., The Dictionary of Drugs: Chemical Data: Chemical Data, Structures, retrieved from:

Pareptide was developed as an antiparkinsonian drug. However, information about the further development of this drug is not available.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Trace analysis of the MIF analogue pareptide in blood plasma by high-performance liquid chromatography and short-wavelength excitation fluorometry.	1979 Aug 21	544604
Determination of the melanotropin-inhibiting factor analogue pareptide in urine by high-performance liquid chromatography.	1981 Mar 13	6112231
Pro-Leu-Gly-NH2 and pareptide inhibit development of tolerance to haloperidol catalepsy in the mouse.	1984 Sep-Oct	6150468
Pharmacological activities of the MIF-1 analogues Pro-Leu-Gly, Tyr-Pro-Leu-Gly and pareptide.	1987 Nov-Dec	2894644

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:08:11 GMT 2023` Edited by `admin` on `Fri Dec 15 16:08:11 GMT 2023`
Record UNII	4743XI19RY
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PAREPTIDE

Official Name

English

pareptide [INN]

Common Name

English

N-(D-1-((CARBAMOYLMETHYL)CARBAMOYL)-3-METHYLBUTYL)-N-METHYL-L-2-PYRROLIDINECARBOXAMIDE

Common Name

English

GLYCINAMIDE, L-PROLYL-N-METHYL-D-LEUCYL-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C38149

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

Code System Code Type Description

INN

4347

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

PRIMARY

PUBCHEM

10086055

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

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EVMPD

SUB09623MIG

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

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ChEMBL

CHEMBL2111011

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

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DAILYMED

4743XI19RY

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

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MESH

C024569

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

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FDA UNII

4743XI19RY

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

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CAS

61484-38-6

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

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NCI_THESAURUS

C66319

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

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EPA CompTox

DTXSID50210450

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

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RXCUI

2619909

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

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SMS_ID

100000082815

Created by admin on Fri Dec 15 16:08:11 GMT 2023 , Edited by admin on Fri Dec 15 16:08:11 GMT 2023

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					4743XI19RY

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