PAREPTIDE SULFATE

Possibly Marketed Outside US

First approved in 2022

Details

Stereochemistry	ABSOLUTE
Molecular Formula	2C14H26N4O3.H2O4S
Molecular Weight	694.841
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OS(O)(=O)=O.CC(C)C[C@@H](N(C)C(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O.CC(C)C[C@@H](N(C)C(=O)[C@@H]2CCCN2)C(=O)NCC(N)=O

InChI

InChIKey=DPOZYRPNCJEMMY-DDRMSGASSA-N

InChI=1S/2C14H26N4O3.H2O4S/c2*1-9(2)7-11(13(20)17-8-12(15)19)18(3)14(21)10-5-4-6-16-10;1-5(2,3)4/h2*9-11,16H,4-8H2,1-3H3,(H2,15,19)(H,17,20);(H2,1,2,3,4)/t2*10-,11+;/m00./s1

HIDE SMILES / InChI

Molecular Formula	C14H26N4O3
Molecular Weight	298.3812
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	H2O4S
Molecular Weight	98.078
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: Elks J., The Dictionary of Drugs: Chemical Data: Chemical Data, Structures, retrieved from:

Pareptide was developed as an antiparkinsonian drug. However, information about the further development of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Pharmacological activities of the MIF-1 analogues Pro-Leu-Gly, Tyr-Pro-Leu-Gly and pareptide.	1987-11-01	2894644
Pro-Leu-Gly-NH2 and pareptide inhibit development of tolerance to haloperidol catalepsy in the mouse.	1984-09-01	6150468
Determination of the melanotropin-inhibiting factor analogue pareptide in urine by high-performance liquid chromatography.	1981-03-13	6112231
Trace analysis of the MIF analogue pareptide in blood plasma by high-performance liquid chromatography and short-wavelength excitation fluorometry.	1979-08-21	544604

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:26:25 GMT 2025` Edited by `admin` on `Mon Mar 31 18:26:25 GMT 2025`
Record UNII	1CMY36S198
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PAREPTIDE SULFATE

Official Name

English

AY-24,856

Preferred Name

English

N-(D-1-((CARBAMOYLMETHYL)CARBAMOYL)-3-METHYLBUTYL)-N-METHYL-L-2-PYRROLIDINECARBOXAMIDE SULFATE (2:1)

Common Name

English

GLYCINAMIDE, L-PROLYL-N-METHYL-D-LEUCYL-, SULFATE (2:1)

Common Name

English

AY-24856

Code

English

N-(D-1-((CARBAMOYLMETHYL)CARBAMOYL)-3-METHYLBUTYL)-N-METHYL-L-2-PYRROLIDINECARBOXAMIDE SULPHATE (2:1)

Common Name

English

PAREPTIDE SULFATE [USAN]

Common Name

English

PAREPTIDE SULPHATE

Common Name

English

GLYCINAMIDE, L-PROLYL-N-METHYL-D-LEUCYL-, SULPHATE (2:1)

Common Name

English

Code System Code Type Description

SMS_ID

300000055572