PAREPTIDE SULFATE

Possibly Marketed Outside US

First approved in 2022

Details

Stereochemistry	ABSOLUTE
Molecular Formula	2C14H26N4O3.H2O4S
Molecular Weight	694.841
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OS(O)(=O)=O.CC(C)C[C@@H](N(C)C(=O)[C@@H]1CCCN1)C(=O)NCC(N)=O.CC(C)C[C@@H](N(C)C(=O)[C@@H]2CCCN2)C(=O)NCC(N)=O

InChI

InChIKey=DPOZYRPNCJEMMY-DDRMSGASSA-N

InChI=1S/2C14H26N4O3.H2O4S/c2*1-9(2)7-11(13(20)17-8-12(15)19)18(3)14(21)10-5-4-6-16-10;1-5(2,3)4/h2*9-11,16H,4-8H2,1-3H3,(H2,15,19)(H,17,20);(H2,1,2,3,4)/t2*10-,11+;/m00./s1

HIDE SMILES / InChI

Molecular Formula	C14H26N4O3
Molecular Weight	298.3812
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	H2O4S
Molecular Weight	98.078
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: Elks J., The Dictionary of Drugs: Chemical Data: Chemical Data, Structures, retrieved from:

Pareptide was developed as an antiparkinsonian drug. However, information about the further development of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Trace analysis of the MIF analogue pareptide in blood plasma by high-performance liquid chromatography and short-wavelength excitation fluorometry.	1979 Aug 21	544604
Determination of the melanotropin-inhibiting factor analogue pareptide in urine by high-performance liquid chromatography.	1981 Mar 13	6112231
Pro-Leu-Gly-NH2 and pareptide inhibit development of tolerance to haloperidol catalepsy in the mouse.	1984 Sep-Oct	6150468
Pharmacological activities of the MIF-1 analogues Pro-Leu-Gly, Tyr-Pro-Leu-Gly and pareptide.	1987 Nov-Dec	2894644

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:22:35 GMT 2023` Edited by `admin` on `Fri Dec 15 16:22:35 GMT 2023`
Record UNII	1CMY36S198
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PAREPTIDE SULFATE

Official Name

English

N-(D-1-((CARBAMOYLMETHYL)CARBAMOYL)-3-METHYLBUTYL)-N-METHYL-L-2-PYRROLIDINECARBOXAMIDE SULFATE (2:1)

Common Name

English

GLYCINAMIDE, L-PROLYL-N-METHYL-D-LEUCYL-, SULFATE (2:1)

Common Name

English

AY-24856

Code

English

N-(D-1-((CARBAMOYLMETHYL)CARBAMOYL)-3-METHYLBUTYL)-N-METHYL-L-2-PYRROLIDINECARBOXAMIDE SULPHATE (2:1)

Common Name

English

PAREPTIDE SULFATE [USAN]

Common Name

English

PAREPTIDE SULPHATE

Common Name

English

AY-24,856

Code

English

GLYCINAMIDE, L-PROLYL-N-METHYL-D-LEUCYL-, SULPHATE (2:1)

Common Name

English

Code System Code Type Description

FDA UNII

1CMY36S198