AZD-3783

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C26H34N4O4
Molecular Weight	466.5726
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC(N2CCN(C)CC2)=C3O[C@H](CCC3=C1)C(=O)NC4=CC=C(C=C4)N5CCOCC5

InChI

InChIKey=SKOWCFJEXPLGNE-XMMPIXPASA-N

InChI=1S/C26H34N4O4/c1-28-9-11-30(12-10-28)23-18-22(32-2)17-19-3-8-24(34-25(19)23)26(31)27-20-4-6-21(7-5-20)29-13-15-33-16-14-29/h4-7,17-18,24H,3,8-16H2,1-2H3,(H,27,31)/t24-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C26H34N4O4
Molecular Weight	466.5726
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:31:34 UTC 2023` Edited by `admin` on `Sat Dec 16 11:31:34 UTC 2023`
Record UNII	3NC9ASE900
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AZD-3783

Common Name

English

AZD 3783 [WHO-DD]

Common Name

English

AZD 3783

Code

English

(2R)-6-METHOXY-8-(4-METHYLPIPERAZIN-1-YL)-N-(4-MORPHOLINOPHENYL)CHROMANE-2-CARBOXAMIDE

Systematic Name

English

AZ-12320927(RACEMATE)

Code

English

(2R)-3,4-DIHYDRO-6-METHOXY-8-(4-METHYL-1-PIPERAZINYL)-N-(4-(4-MORPHOLINYL)PHENYL)-2H-1-BENZOPYRAN-2-CARBOXAMIDE

Systematic Name

English

2H-1-BENZOPYRAN-2-CARBOXAMIDE, 3,4-DIHYDRO-6-METHOXY-8-(4-METHYL-1-PIPERAZINYL)-N-(4-(4-MORPHOLINYL)PHENYL)-, (2R)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

25067561

Created by admin on Sat Dec 16 11:31:34 UTC 2023 , Edited by admin on Sat Dec 16 11:31:34 UTC 2023

PRIMARY

FDA UNII

3NC9ASE900

Created by admin on Sat Dec 16 11:31:34 UTC 2023 , Edited by admin on Sat Dec 16 11:31:34 UTC 2023

PRIMARY

CAS

1162658-64-1

Created by admin on Sat Dec 16 11:31:34 UTC 2023 , Edited by admin on Sat Dec 16 11:31:34 UTC 2023

PRIMARY

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					3NC9ASE900

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					3NC9ASE900

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ACTIVE MOIETY

Comments:

In the 3-month study, neurotoxicity resulted in euthanasia of one animal dosed at 30 mg/kg/day after 86 days.