TRITROMETHAMINE GUANOSINE TRIPHOSPHATE

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C10H12N5O14P3.3C4H11NO3.4H
Molecular Weight	886.5855
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TRITROMETHAMINE GUANOSINE TRIPHOSPHATE

Structure Search

SMILES

[H+].[H+].[H+].[H+].NC(CO)(CO)CO.NC(CO)(CO)CO.NC(CO)(CO)CO.NC1=NC2=C(N=CN2[C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1

InChI

InChIKey=UXNOYHQEVMMTDK-CYCLDIHTSA-N

InChI=1S/C10H16N5O14P3.3C4H11NO3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;3*5-4(1-6,2-7)3-8/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);3*6-8H,1-3,5H2/t3-,5-,6-,9-;;;/m1.../s1

HIDE SMILES / InChI

Molecular Formula	H
Molecular Weight	1.0079
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C10H12N5O14P3
Molecular Weight	519.1487
Charge	-4
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	C4H11NO3
Molecular Weight	121.135
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
UMP-CMP kinase 5 Target ID: CHEMBL5681 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8573186	Substrate 661
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 5 Target ID: Q9Y3Z3 Gene ID: 25939.0 Gene Symbol: SAMHD1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/23880768	Activator 1430
Ras-like GTPases 5 Target ID: Ras-like GTPases Sources: https://www.ncbi.nlm.nih.gov/pubmed/15236956	Substrate 661

PubMed

Title	Date	PubMed
[Mechanism of the activating action of guanosine triphosphate (GTP) on the fat oxidazing enzyme system. IV].	1959 Feb 15	13639918
Phosphoenolpyruvate carboxykinase (guanosine triphosphate) from rat liver cytosol. Separation of homogeneous forms of the enzyme with high and low activity by chromatography on agarose-hexane-guanosine triphosphate.	1978 Dec 12	728402
GTP is the primary activator of the anti-HIV restriction factor SAMHD1.	2013 Aug 30	23880768

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:41:49 GMT 2023` Edited by `admin` on `Sat Dec 16 11:41:49 GMT 2023`
Record UNII	3MCN98DO06
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRITROMETHAMINE GUANOSINE TRIPHOSPHATE

Common Name

English

TRITROMETHAMINE GUANOSINE 5'-TRIPHOSPHATE

Common Name

English

GUANOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), COMPD. WITH 2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL (1:3)

Systematic Name

English

1,3-PROPANEDIOL, 2-AMINO-2-(HYDROXYMETHYL)-, COMPD. WITH GUANOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE) (3:1)

Systematic Name

English

GUANOSINE-5'-TRIPHOSPHATE TRIS SALT

Common Name

English

Code System Code Type Description

CAS

103192-46-7

Created by admin on Sat Dec 16 11:41:49 GMT 2023 , Edited by admin on Sat Dec 16 11:41:49 GMT 2023

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FDA UNII

3MCN98DO06

Created by admin on Sat Dec 16 11:41:49 GMT 2023 , Edited by admin on Sat Dec 16 11:41:49 GMT 2023

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EPA CompTox

DTXSID90745635

Created by admin on Sat Dec 16 11:41:49 GMT 2023 , Edited by admin on Sat Dec 16 11:41:49 GMT 2023

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PUBCHEM

135564988

Created by admin on Sat Dec 16 11:41:49 GMT 2023 , Edited by admin on Sat Dec 16 11:41:49 GMT 2023

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GUANOSINE TRIPHOSPHATE

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