U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula Xe
Molecular Weight 131.293
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of XENON

SMILES

[Xe]

InChI

InChIKey=FHNFHKCVQCLJFQ-UHFFFAOYSA-N
InChI=1S/Xe

HIDE SMILES / InChI

Molecular Formula Xe
Molecular Weight 131.293
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Xenon is a noble gas used as an anesthetic agent. Xenon can associate with amino acid side chains of the active site of enzymes such as serine proteinases (including elastases and collagenases); these enzymes can form a specific binding cavity for single xenon atom without inducing major changes in protein structure. It has been demonstrated that xenon binds within the heme cavity of cytochrome P-450 monooxygenases and is capable of inhibiting the catalytic activity of some enzymes in vitro. Current evidence suggests that inhibition of N-methyl-D-aspartate (NMDA) receptor signaling is the mechanism by which xenon induces anesthesia. Although approved for use in anesthesia in Russia in 2000, it was unavailable for use in western countries until October 2005 when approval for its use was granted in Germany.

Approval Year

PubMed

PubMed

TitleDatePubMed
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:02:11 UTC 2023
Edited
by admin
on Fri Dec 15 16:02:11 UTC 2023
Record UNII
3H3U766W84
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
XENON
JAN   MART.   MI   VANDF   WHO-DD  
Systematic Name English
XENON [MI]
Common Name English
XENON [JAN]
Common Name English
XENON [VANDF]
Common Name English
XENON [MART.]
Common Name English
Xenon [WHO-DD]
Common Name English
Classification Tree Code System Code
WHO-VATC QN01AX15
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
FDA ORPHAN DRUG 461914
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
EU-Orphan Drug EU/3/16/1768
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
FDA ORPHAN DRUG 455714
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
NCI_THESAURUS C1940
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
WHO-ATC N01AX15
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
Code System Code Type Description
FDA UNII
3H3U766W84
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
DRUG CENTRAL
4369
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
DRUG BANK
DB13453
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
PUBCHEM
23991
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
LACTMED
Xenon
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
EVMPD
SUB32179
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
SMS_ID
100000127076
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
MESH
D014978
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
RXCUI
11363
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY RxNorm
EPA CompTox
DTXSID5064700
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
WIKIPEDIA
Xenon
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
NCI_THESAURUS
C85247
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
CHEBI
49957
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
MERCK INDEX
m11540
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY Merck Index
CHEBI
49956
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
CAS
7440-63-3
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
ECHA (EC/EINECS)
231-172-7
Created by admin on Fri Dec 15 16:02:11 UTC 2023 , Edited by admin on Fri Dec 15 16:02:11 UTC 2023
PRIMARY
Related Record Type Details
SOLVATE->ANHYDROUS
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY