Vixticibart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 19:33:27 GMT 2025` Edited by `admin` on `Wed Apr 02 19:33:27 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	3E5N6X8CJF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

REGN-5381

Preferred Name

English

Vixticibart

Official Name

English

H-gamma4 heavy chain Homo sapiens(1-451) [VH (Homo sapiens IGHV1-2*02 (91.8%) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (125-222), hinge 1-12 S10>P (232) (223-234), C

Common Name

English

Immunoglobulin G4 [232-proline], anti-(human natriuretic peptide receptor A) (human monoclonal REGN5381 ?4-chain), disulfide with human monoclonal REGN5381 ?-chain, dimer

Common Name

English

vixticibart [INN]

Common Name

English

immunoglobulin G4-kappa, anti-[Homo sapiens NPR1 (natriuretic peptide receptor 1, natriuretic peptide receptor A, NPRA, atrionatriuretic peptide receptor A, ANPRA, guanylate cyclase A, GUCY2A)], Homo sapiens monoclonal antibody, agonist

Common Name

English

REGN5381

Code

English

Code System Code Type Description

CAS

2794175-82-7