U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:12:34 GMT 2023
Edited
by admin
on Sat Dec 16 15:12:34 GMT 2023
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
3DV5TD1VL3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Sacituzumab tirumotecan
INN  
Official Name English
sacituzumab tirumotecan [INN]
Common Name English
Immunoglobulin G1-kappa, anti-[Homo sapiens TACSTD2 (tumor-associated calcium signal transducer 2, membrane component chromosome 1 surface marker 1, M1S1, gastrointestinal tumor-associated antigen GA7331, pancreatic carcinoma marker protein GA733-1, epit
Common Name English
Immunoglobulin G1, anti-(human tumor-associated calcium signal transducer 2) (human-Mus musculus monoclonal hRS7 γ1-chain), disulfide with human-Mus musculus monoclonal hRS7 κ-chain, dimer, reduced, S-[5-[6-[[[1-[(34S)-38-amino-34-[[[4-[[[[[(4S)-4-ethy
Common Name English
Code System Code Type Description
CAS
2768350-77-0
Created by admin on Sat Dec 16 15:12:34 GMT 2023 , Edited by admin on Sat Dec 16 15:12:34 GMT 2023
PRIMARY
FDA UNII
3DV5TD1VL3
Created by admin on Sat Dec 16 15:12:34 GMT 2023 , Edited by admin on Sat Dec 16 15:12:34 GMT 2023
PRIMARY
INN
12801
Created by admin on Sat Dec 16 15:12:34 GMT 2023 , Edited by admin on Sat Dec 16 15:12:34 GMT 2023
PRIMARY
From To
1_22 1_96
1_148 1_204
1_224 3_214
1_230 2_230
1_233 2_233
1_265 1_325
1_371 1_429
2_22 2_96
2_148 2_204
2_224 4_214
2_265 2_325
2_371 2_429
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_301
N 2_301
Related Record Type Details
CONJUGATE COMPONENT->CONJUGATE
TARGET -> INHIBITOR
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL