METHCATHINONE

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C10H13NO
Molecular Weight	163.2163
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNC(C)C(=O)C1=CC=CC=C1

InChI

InChIKey=LPLLVINFLBSFRP-UHFFFAOYSA-N

InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3

HIDE SMILES / InChI

Molecular Formula	C10H13NO
Molecular Weight	163.2163
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

PubMed

Title	Date	PubMed
Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428.	1998 Oct 15	9763484
High-performance liquid chromatographic method development and validation for the simultaneous quantitation of naproxen sodium and pseudoephedrine hydrochloride impurities.	2001 Mar	11277256
Cathinone (Khat) and methcathinone (CAT) in urine specimens: a gas chromatographic-mass spectrometric detection procedure.	2001 Oct	11599595
Inhibition of transport function and desipramine binding at the human noradrenaline transporter by N-ethylmaleimide and protection by substrate analogs.	2002 Jun	12070759
Methcathinone is a substrate for the serotonin uptake transporter.	2003 Nov	14629733
In vitro characterization of ephedrine-related stereoisomers at biogenic amine transporters and the receptorome reveals selective actions as norepinephrine transporter substrates.	2003 Oct	12954796
Simultaneous determination of eight underivatized amphetamines in hair by high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry (HPLC-APCI-MS).	2004 Mar	15068560
[Methcathinone poisoning associated with bromazepam and alcohol].	2004 Mar-Apr	15359625
Methcathinone: a new postindustrial drug.	2005 Oct 4	15919169
Interactions of cocaine with dopamine uptake inhibitors or dopamine releasers in rats discriminating cocaine.	2006 Jun	16478825
Simultaneous determination of psychotropic phenylalkylamine derivatives in human hair by gas chromatography/mass spectrometry.	2007	17474080
Detection and validated quantification of nine herbal phenalkylamines and methcathinone in human blood plasma by LC-MS/MS with electrospray ionization.	2007 Feb	17154352
Effects of topiramate on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition in recently abstinent methamphetamine-dependent individuals.	2007 Jan 30	16978753
[Drugs and desperation in different worlds. Abuse of cathinone and methcathinone].	2009 May 13-19	19585829
Breaking the news or fueling the epidemic? Temporal association between news media report volume and opioid-related mortality.	2009 Nov 18	19924221
Substance abuse and movement disorders.	2009 Sep	20443774
Multiple-drug toxicity caused by the coadministration of 4-methylmethcathinone (mephedrone) and heroin.	2010 Apr	20406541
LC-MS/MS screening method for designer amphetamines, tryptamines, and piperazines in serum.	2010 Apr	20069283
Manganese and Parkinson's disease: a critical review and new findings.	2010 Aug	20403794
White matter abnormalities in methcathinone abusers with an extrapyramidal syndrome.	2010 Dec	21036949
Manganese inhalation as a Parkinson disease model.	2010 Dec 19	21209715
Selective vulnerability in striosomes and in the nigrostriatal dopaminergic pathway after methamphetamine administration : early loss of TH in striosomes after methamphetamine.	2010 Jul	19760475
White-matter abnormalities in brain during early abstinence from methamphetamine abuse.	2010 Mar	20101394
Amphetamine dependence and co-morbid alcohol abuse: associations to brain cortical thickness.	2010 May 20	20487539
Peripheral blood RNA expression profiling in illicit methcathinone users reveals effect on immune system.	2011	22303338
Manganese-Induced Parkinsonism Is Not Idiopathic Parkinson's Disease: Environmental and Genetic Evidence.	2015 Aug	26220508

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:39:03 GMT 2023` Edited by `admin` on `Sat Dec 16 08:39:03 GMT 2023`
Record UNII	386QA522QG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

METHCATHINONE

Common Name

English

METHCATHINONE [MI]

Common Name

English

1-PROPANONE, 2-(METHYLAMINO)-1-PHENYL-

Systematic Name

English

UR-1431

Code

English

J31.084K

Code

English

MONOMETHYLPROPION

Common Name

English

1-PHENYL-2-METHYLAMINO-1-PROPANONE

Systematic Name

English

EPHEDRONE

Common Name

English

(±)-METHCATHINONE

Common Name

English

JEE COCKTAIL

Common Name

English

1-PHENYL-1-OXO-2-METHYLAMINOPROPANE

Systematic Name

English

JEFF

Common Name

English

MULKA

Common Name

English

COSMOS

Common Name

English

Classification Tree Code System Code

DEA NO.

1237