HEXAMIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H26N4O2
Molecular Weight	354.446
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

NC(=N)C1=CC=C(OCCCCCCOC2=CC=C(C=C2)C(N)=N)C=C1

InChI

InChIKey=OQLKNTOKMBVBKV-UHFFFAOYSA-N

InChI=1S/C20H26N4O2/c21-19(22)15-5-9-17(10-6-15)25-13-3-1-2-4-14-26-18-11-7-16(8-12-18)20(23)24/h5-12H,1-4,13-14H2,(H3,21,22)(H3,23,24)

HIDE SMILES / InChI

Molecular Formula	C20H26N4O2
Molecular Weight	354.446
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

Hexamidine diisethionate has been used in the personal care industry and in a number of over-the-counter (OTC) drug products as an antimicrobial agent. It was shown, that hexamidine diisethionate plays a beneficial role in skin homoeostasis.

Approval Year

PubMed

Show entries

Title	Date	PubMed
Opportunistic amoebae: challenges in prophylaxis and treatment.	2004 Feb	15072770
[Clinical tolerance of cutaneous antiseptics in 3,403 patients in France].	2006 Oct	17072189
Final report on the safety assessment of Hexamidine and Hexamidine Diisethionate.	2007	18273451
[Acanthamoeba keratitis: about the first two Tunisian cases].	2007 Feb	17402694
Visual outcome and rehabilitation in a case of bilateral acanthamoeba sclerokeratitis.	2007 Oct	17893557