CAMYLOFIN

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H32N2O2
Molecular Weight	320.4696
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN(CC)CCNC(C(=O)OCCC(C)C)C1=CC=CC=C1

InChI

InChIKey=RYOOHIUJEJZCFT-UHFFFAOYSA-N

InChI=1S/C19H32N2O2/c1-5-21(6-2)14-13-20-18(17-10-8-7-9-11-17)19(22)23-15-12-16(3)4/h7-11,16,18,20H,5-6,12-15H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C19H32N2O2
Molecular Weight	320.4696
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: http://www.drugsupdate.com/generic/view/753/Camylofin
Curator's Comment: Description was created based on several sources, including http://www.ijrcog.org/index.php/ijrcog/article/view/1419

Camylofin is an antimuscarinic. This medication is used as antispasmodic in biliary colic, renal and ureteric colic, dysmenorrhoea, peptic ulcer and chronic enterocolitis. It is used to treat stomach ache in infants and children. Camylofin should be the first choice and may be preferred over other drugs for cervical dilatation and acceleration of active phase of labor.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Muscarinic acetylcholine receptor 160 Target ID: CHEMBL2094109 Sources: http://www.genome.jp/dbget-bin/www_bget?dr:D07076	Antagonist 2778

Conditions

Condition	Modality	Targets	Highest Phase	Product
Labor complications 8 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22895986 https://www.ncbi.nlm.nih.gov/pubmed/23737030 https://www.ncbi.nlm.nih.gov/pubmed/24179892 http://www.ijrcog.org/index.php/ijrcog/article/view/1419	Primary		Approved 8429	ANAFORTAN Approved Use Camylofin is used as an anti-spasmodic. Camylofin is primarily indicated in conditions like Angina, Biliary colic, Dysmenorrhoea, Migraine, Myocardial infarction, Pancreatitis, Renal colic, Spasticity.
Spasm 18 Sources: http://www.druginfosys.com/drug.aspx?drugcode=833&type=1 http://www.medclik.com/General/pages/Drugmanual/BrandSearch/ANAFORTAN.asp	Primary		Approved 8429	ANAFORTAN Approved Use Camylofin is used as an anti-spasmodic. Camylofin is primarily indicated in conditions like Angina, Biliary colic, Dysmenorrhoea, Migraine, Myocardial infarction, Pancreatitis, Renal colic, Spasticity.

PubMed

Title	Date	PubMed
A study of metabolism of isoamyl alpha-[N-(beta-diethylamino-ethyl)]-aminophenylacetate (avacan).	1956 Mar	13331655

Patents

Sample Use Guides

In Vivo Use Guide

0.285 to 0.857 mg/kg to be taken every 8 hrs.

Route of Administration: Other

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:13:00 GMT 2023` Edited by `admin` on `Fri Dec 15 17:13:00 GMT 2023`
Record UNII	340B6Q764V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CAMYLOFIN

Official Name

English

ANAFORTAN

Brand Name

English

ACAMYLOPHENINE

Common Name

English

N-(2-(DIETHYLAMINO)ETHYL)-2-PHENYLGLYCINE, ISOPENTYL ESTER

Common Name

English

CAMYLOFINE [MI]

Common Name

English

camylofin [INN]

Common Name

English

Camylofin [WHO-DD]

Common Name

English

CAMYLOFINE

Common Name

English

Classification Tree Code System Code

WHO-VATC

QA03DA05