Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C24H33N |
| Molecular Weight | 335.5255 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(CC1CCCCC1)NCCC(C2=CC=CC=C2)C3=CC=CC=C3
InChI
InChIKey=HTAFVGKAHGNWQO-UHFFFAOYSA-N
InChI=1S/C24H33N/c1-20(19-21-11-5-2-6-12-21)25-18-17-24(22-13-7-3-8-14-22)23-15-9-4-10-16-23/h3-4,7-10,13-16,20-21,24-25H,2,5-6,11-12,17-19H2,1H3
| Molecular Formula | C24H33N |
| Molecular Weight | 335.5255 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Droprenilamine hydrochloride is coronary vasodilator. It is a secondary amine structurally related to the antianginal drug prenylamine. It increases coronary flow in the isolated guinea-pig heart and partially inhibits pitressin-induced ST-segment changes in anaesthetized rats. Droprenilamine hydrochloride also elevated coronary blood flow in the anaesthetized greyhound and reduced the incidence of cardiac dysrhythmias, which result from acute ligation of the anterior descending branch of the left coronary artery. Droprenilamine hydrochloride only reduced heart rate when administered after coronary artery occlusion, a fact, which may be related to the effects of the drug on the increased sympatho-adrenal outflow produced by myocardial ischemia.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:39:06 GMT 2023
by
admin
on
Fri Dec 15 16:39:06 GMT 2023
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| Record UNII |
31IPX0ZD7R
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29707
Created by
admin on Fri Dec 15 16:39:06 GMT 2023 , Edited by admin on Fri Dec 15 16:39:06 GMT 2023
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3167
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65470
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C65488
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100000081026
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31IPX0ZD7R
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57653-27-7
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CHEMBL2106278
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DTXSID10866639
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SUB06411MIG
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m1125
Created by
admin on Fri Dec 15 16:39:06 GMT 2023 , Edited by admin on Fri Dec 15 16:39:06 GMT 2023
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PRIMARY | Merck Index | ||
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4026
Created by
admin on Fri Dec 15 16:39:06 GMT 2023 , Edited by admin on Fri Dec 15 16:39:06 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ENANTIOMER -> RACEMATE | |||
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SALT/SOLVATE -> PARENT | |||
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ENANTIOMER -> RACEMATE |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
