Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C24H33N.ClH |
| Molecular Weight | 371.986 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CC(CC1CCCCC1)NCCC(C2=CC=CC=C2)C3=CC=CC=C3
InChI
InChIKey=HDIWDSZQIUBDFT-UHFFFAOYSA-N
InChI=1S/C24H33N.ClH/c1-20(19-21-11-5-2-6-12-21)25-18-17-24(22-13-7-3-8-14-22)23-15-9-4-10-16-23;/h3-4,7-10,13-16,20-21,24-25H,2,5-6,11-12,17-19H2,1H3;1H
| Molecular Formula | C24H33N |
| Molecular Weight | 335.5255 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Droprenilamine hydrochloride is coronary vasodilator. It is a secondary amine structurally related to the antianginal drug prenylamine. It increases coronary flow in the isolated guinea-pig heart and partially inhibits pitressin-induced ST-segment changes in anaesthetized rats. Droprenilamine hydrochloride also elevated coronary blood flow in the anaesthetized greyhound and reduced the incidence of cardiac dysrhythmias, which result from acute ligation of the anterior descending branch of the left coronary artery. Droprenilamine hydrochloride only reduced heart rate when administered after coronary artery occlusion, a fact, which may be related to the effects of the drug on the increased sympatho-adrenal outflow produced by myocardial ischemia.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:30:55 GMT 2023
by
admin
on
Sat Dec 16 09:30:55 GMT 2023
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| Record UNII |
OG73JS161X
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| Record Status |
Validated (UNII)
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| Record Version |
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59182-63-7
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65471
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m1125
Created by
admin on Sat Dec 16 09:30:55 GMT 2023 , Edited by admin on Sat Dec 16 09:30:55 GMT 2023
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OG73JS161X
Created by
admin on Sat Dec 16 09:30:55 GMT 2023 , Edited by admin on Sat Dec 16 09:30:55 GMT 2023
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DTXSID40974615
Created by
admin on Sat Dec 16 09:30:55 GMT 2023 , Edited by admin on Sat Dec 16 09:30:55 GMT 2023
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| Related Record | Type | Details | ||
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ENANTIOMER -> RACEMATE | |||
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ENANTIOMER -> RACEMATE | |||
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PARENT -> SALT/SOLVATE |
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ACTIVE MOIETY |