Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C24H33N.ClH |
| Molecular Weight | 371.986 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CC(CC1CCCCC1)NCCC(C2=CC=CC=C2)C3=CC=CC=C3
InChI
InChIKey=HDIWDSZQIUBDFT-UHFFFAOYSA-N
InChI=1S/C24H33N.ClH/c1-20(19-21-11-5-2-6-12-21)25-18-17-24(22-13-7-3-8-14-22)23-15-9-4-10-16-23;/h3-4,7-10,13-16,20-21,24-25H,2,5-6,11-12,17-19H2,1H3;1H
| Molecular Formula | C24H33N |
| Molecular Weight | 335.5255 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Droprenilamine hydrochloride is coronary vasodilator. It is a secondary amine structurally related to the antianginal drug prenylamine. It increases coronary flow in the isolated guinea-pig heart and partially inhibits pitressin-induced ST-segment changes in anaesthetized rats. Droprenilamine hydrochloride also elevated coronary blood flow in the anaesthetized greyhound and reduced the incidence of cardiac dysrhythmias, which result from acute ligation of the anterior descending branch of the left coronary artery. Droprenilamine hydrochloride only reduced heart rate when administered after coronary artery occlusion, a fact, which may be related to the effects of the drug on the increased sympatho-adrenal outflow produced by myocardial ischemia.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:42:12 GMT 2025
by
admin
on
Mon Mar 31 22:42:12 GMT 2025
|
| Record UNII |
OG73JS161X
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Preferred Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
59182-63-7
Created by
admin on Mon Mar 31 22:42:12 GMT 2025 , Edited by admin on Mon Mar 31 22:42:12 GMT 2025
|
PRIMARY | |||
|
65471
Created by
admin on Mon Mar 31 22:42:12 GMT 2025 , Edited by admin on Mon Mar 31 22:42:12 GMT 2025
|
PRIMARY | |||
|
m1125
Created by
admin on Mon Mar 31 22:42:12 GMT 2025 , Edited by admin on Mon Mar 31 22:42:12 GMT 2025
|
PRIMARY | Merck Index | ||
|
OG73JS161X
Created by
admin on Mon Mar 31 22:42:12 GMT 2025 , Edited by admin on Mon Mar 31 22:42:12 GMT 2025
|
PRIMARY | |||
|
DTXSID40974615
Created by
admin on Mon Mar 31 22:42:12 GMT 2025 , Edited by admin on Mon Mar 31 22:42:12 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ENANTIOMER -> RACEMATE | |||
|
|
ENANTIOMER -> RACEMATE | |||
|
|
PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |