ACEDIASULFONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H14N2O4S
Molecular Weight	306.337
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ACEDIASULFONE

Structure Search

SMILES

NC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(NCC(O)=O)C=C2

InChI

InChIKey=FKKUMFTYSTZUJG-UHFFFAOYSA-N

InChI=1S/C14H14N2O4S/c15-10-1-5-12(6-2-10)21(19,20)13-7-3-11(4-8-13)16-9-14(17)18/h1-8,16H,9,15H2,(H,17,18)

HIDE SMILES / InChI

Molecular Formula	C14H14N2O4S
Molecular Weight	306.337
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=Cz3GGv5OqJwC&pg=PA328&lpg=PA328&dq=ACEDIASULFONE+dapsone&source=bl&ots=mz9uH4e5EG&sig=ACfU3U1PtEtvS3yOIa4d4zWbbacR3eemvw&hl=ru&sa=X&ved=2ahUKEwi5tJLPv8bhAhXAxMQBHS_OBZYQ6AEwBnoECAYQAQ#v=onepage&q=ACEDIASULFONE%20dapsone&f=false

Acedia Sulfone, an antimicrobial drug that is a prodrug of dapsone, which is used to treat leprosy.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Column and thin-layer chromatographic methods for the simultaneous determination of acediasulfone in the presence of cinchocaine, and cefuroxime in the presence of its hydrolytic degradation products.	2007-05-04	17474511
Folate-synthesizing enzyme system as target for development of inhibitors and inhibitor combinations against Candida albicans-synthesis and biological activity of new 2,4-diaminopyrimidines and 4'-substituted 4-aminodiphenyl sulfones.	2004-01-01	14695838
Evaluation of the sulfones and streptomycin in experimental tuberculosis.	1949-12-14	15398779

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:23:11 GMT 2025` Edited by `admin` on `Mon Mar 31 18:23:11 GMT 2025`
Record UNII	30YP2YHH8W
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ACEDIASULFONE [MI]

Preferred Name

English

ACEDIASULFONE

Common Name

English

N-P-SULFANILYLPHENYLGLYCINE

Common Name

English

ACEDIASULPHONE

Common Name

English

Acediasulfone [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C849

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

Code System Code Type Description

WIKIPEDIA

ACEDIASULFONE

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

DRUG BANK

DB08926

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

NCI_THESAURUS

C77129

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

EVMPD

SUB00242MIG

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

FDA UNII

30YP2YHH8W

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

MERCK INDEX

m1294

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

Merck Index

CAS

80-03-5

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

SMS_ID

100000078805

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

PUBCHEM

66451

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

ECHA (EC/EINECS)

201-243-7

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

DRUG CENTRAL

44

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

MESH

C521214

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

EPA CompTox

DTXSID00229991

Created by admin on Mon Mar 31 18:23:11 GMT 2025 , Edited by admin on Mon Mar 31 18:23:11 GMT 2025

PRIMARY

Related Record Type Details


					M45G7BJL52

ACEDIASULFONE SODIUM

SALT/SOLVATE -> PARENT

Related Record Type Details


					30YP2YHH8W

ACTIVE MOIETY