ACEDIASULFONE SODIUM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H13N2O4S.Na
Molecular Weight	328.319
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].NC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(NCC([O-])=O)C=C2

InChI

InChIKey=GPNYXGDUKNYCNI-UHFFFAOYSA-M

InChI=1S/C14H14N2O4S.Na/c15-10-1-5-12(6-2-10)21(19,20)13-7-3-11(4-8-13)16-9-14(17)18;/h1-8,16H,9,15H2,(H,17,18);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C14H13N2O4S
Molecular Weight	305.329
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=Cz3GGv5OqJwC&pg=PA328&lpg=PA328&dq=ACEDIASULFONE+dapsone&source=bl&ots=mz9uH4e5EG&sig=ACfU3U1PtEtvS3yOIa4d4zWbbacR3eemvw&hl=ru&sa=X&ved=2ahUKEwi5tJLPv8bhAhXAxMQBHS_OBZYQ6AEwBnoECAYQAQ#v=onepage&q=ACEDIASULFONE%20dapsone&f=false

Acedia Sulfone, an antimicrobial drug that is a prodrug of dapsone, which is used to treat leprosy.

Approval Year

PubMed

Title	Date	PubMed
Evaluation of the sulfones and streptomycin in experimental tuberculosis.	1949 Dec 14	15398779
Folate-synthesizing enzyme system as target for development of inhibitors and inhibitor combinations against Candida albicans-synthesis and biological activity of new 2,4-diaminopyrimidines and 4'-substituted 4-aminodiphenyl sulfones.	2004 Jan 1	14695838
Column and thin-layer chromatographic methods for the simultaneous determination of acediasulfone in the presence of cinchocaine, and cefuroxime in the presence of its hydrolytic degradation products.	2007 Mar-Apr	17474511

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:28:07 GMT 2023` Edited by `admin` on `Fri Dec 15 15:28:07 GMT 2023`
Record UNII	M45G7BJL52
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ACEDIASULFONE SODIUM

Official Name

English

NSC-158324

Code

English

ACEDIASULFONE SODIUM [MART.]

Common Name

English

acediasulfone sodium [INN]

Common Name

English

Acediasulfone sodium [WHO-DD]

Common Name

English

DERMAC JABON

Brand Name

English

ACEDIASULPHONE SODIUM

Common Name

English

ACEDIASULFONE SODIUM SALT

Common Name

English

ACEDIASULFONE SODIUM SALT [MI]

Common Name

English

N-P-SULFANILYLPHENYLGLYCINE SODIUM

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C849