Omoprubart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 20:08:42 GMT 2023` Edited by `admin` on `Sat Dec 16 20:08:42 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG2\|IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	2YUH7KM2C2
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Omoprubart

Official Name

English

gamma2/gamma4 heavy chain (1-448) [VH (Homo sapiens IGHV1-2*06 (85.7%) -(IGHD) -IGHJ4*01(93.3%), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG2*01 CH1-hinge (CH1 (123-220), hinge 1-15 (221-232)) -Homo sapiens IGHG4*01CH2-CH3, nG4m(a)

Common Name

English

CAN-106

Code

English

CAN106

Code

English

Immunoglobulin G [27-histidine,57-histidine,253-tyrosine,255-threonine,257-glutamic acid], anti-(human complement C5) (human monoclonal CAN106 hybrid γ2-chain CH1-hinge region/γ4-chain CH2-CH3 region), disulfide with human monoclonal CAN106 κ-chain, d

Common Name

English

mmunoglobulin G2/G4-kappa, anti-[Homo sapiens C5 (complement 5)], monoclonal antibody

Common Name

English

omoprubart [INN]

Common Name

English

Code System Code Type Description

FDA UNII

2YUH7KM2C2

Created by admin on Sat Dec 16 20:08:42 GMT 2023 , Edited by admin on Sat Dec 16 20:08:42 GMT 2023

PRIMARY

INN

12638

Created by admin on Sat Dec 16 20:08:42 GMT 2023 , Edited by admin on Sat Dec 16 20:08:42 GMT 2023

PRIMARY

CAS

2763342-87-4

Created by admin on Sat Dec 16 20:08:42 GMT 2023 , Edited by admin on Sat Dec 16 20:08:42 GMT 2023

PRIMARY

From	To
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
1_231	2_231
1_228	2_228
1_225	2_225
1_224	2_224
2_136	4_214
1_136	3_214
2_368	2_426
2_262	2_322
2_149	2_205
2_22	2_96
1_368	1_426
1_262	1_322
1_149	1_205
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					7A6G4V3R84

COMPLEMENT C5

TARGET->LIGAND

Amount:

Related Record Type Details


					2YUH7KM2C2

Omoprubart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL