BMS-561392

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H32N4O4
Molecular Weight	476.5674
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)C[C@@H](N1CC[C@](N)(C1=O)C2=CC=C(OCC3=CC(C)=NC4=CC=CC=C34)C=C2)C(=O)NO

InChI

InChIKey=QVNZBDLTUKCPGJ-SHQCIBLASA-N

InChI=1S/C27H32N4O4/c1-17(2)14-24(25(32)30-34)31-13-12-27(28,26(31)33)20-8-10-21(11-9-20)35-16-19-15-18(3)29-23-7-5-4-6-22(19)23/h4-11,15,17,24,34H,12-14,16,28H2,1-3H3,(H,30,32)/t24-,27-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C27H32N4O4
Molecular Weight	476.5674
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Effect of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide], a human tumor necrosis factor alpha-converting enzyme inhibitor, on the disposition of methotrexate: a transporter-based drug-drug interaction case study.	2007 Jun	17332143

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:06:24 GMT 2023` Edited by `admin` on `Sat Dec 16 09:06:24 GMT 2023`
Record UNII	2X066A8676
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BMS-561392

Common Name

English

DPC-333

Code

English

BMS561392

Code

English

(2R)-2-((3R)-3-AMINO-3-(4-((2-METHYL-4-QUINOLINYL)METHOXY)PHENYL)-2-OXO-1-PYRROLIDINYL)-N-HYDROXY-4-METHYLPENTANAMIDE

Systematic Name

English

Code System Code Type Description

CAS

611227-74-8