U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C11H23N7
Molecular Weight 253.3472
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MELADRAZINE

SMILES

CCN(CC)C1=NC(=NN)N=C(N1)N(CC)CC

InChI

InChIKey=IRQOBYXMACIFKD-UHFFFAOYSA-N
InChI=1S/C11H23N7/c1-5-17(6-2)10-13-9(16-12)14-11(15-10)18(7-3)8-4/h5-8,12H2,1-4H3,(H,13,14,15,16)

HIDE SMILES / InChI

Molecular Formula C11H23N7
Molecular Weight 253.3472
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Meladrazine is a drug used in urology as an antispasmodic. Meladrazine acts on the central nervous system as a polysynaptic inhibitor. Its usefulness in treating spasticity in patients with multiple sclerosis is well known. As many of these patients have bladder problems, a coincidental beneficial effect on uninhibited bladders has been discovered. Meladrazine caused a high incidence of side effects; therefore, treatment with terodiline separately is recommended for geriatric patients who have severe motor urge incontinence.

Approval Year

PubMed

PubMed

TitleDatePubMed
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:23:29 GMT 2023
Edited
by admin
on Fri Dec 15 16:23:29 GMT 2023
Record UNII
2V6Z0JG2X0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MELADRAZINE
INN   WHO-DD  
INN  
Official Name English
meladrazine [INN]
Common Name English
Meladrazine [WHO-DD]
Common Name English
2,4-BIS(DIETHYLAMINO)-6-HYDRAZINO-S-TRIAZINE
Systematic Name English
BA 13155 FREE BASE
Code English
HYDRAMITRAZINE [MI]
Common Name English
NSC-99857
Code English
BA-13155 FREE BASE
Code English
Classification Tree Code System Code
NCI_THESAURUS C29698
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
WHO-VATC QG04BD03
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
WHO-ATC G04BD03
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
Code System Code Type Description
FDA UNII
2V6Z0JG2X0
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
EPA CompTox
DTXSID20161107
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
PUBCHEM
71679
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
NSC
99857
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
SMS_ID
100000081444
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
DRUG BANK
DB13272
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
DRUG CENTRAL
3756
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
ECHA (EC/EINECS)
237-736-9
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
WIKIPEDIA
MELADRAZINE
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
MERCK INDEX
m238
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY Merck Index
CAS
13957-36-3
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
NCI_THESAURUS
C66076
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
EVMPD
SUB08717MIG
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
INN
1798
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
MESH
C005040
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
ChEMBL
CHEMBL2105242
Created by admin on Fri Dec 15 16:23:29 GMT 2023 , Edited by admin on Fri Dec 15 16:23:29 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY