MELADRAZINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H23N7
Molecular Weight	253.3472
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MELADRAZINE

Structure Search

SMILES

CCN(CC)C1=NC(=NN)N=C(N1)N(CC)CC

InChI

InChIKey=IRQOBYXMACIFKD-UHFFFAOYSA-N

InChI=1S/C11H23N7/c1-5-17(6-2)10-13-9(16-12)14-11(15-10)18(7-3)8-4/h5-8,12H2,1-4H3,(H,13,14,15,16)

HIDE SMILES / InChI

Molecular Formula	C11H23N7
Molecular Weight	253.3472
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3880780 | https://www.ncbi.nlm.nih.gov/pubmed/19160231 | https://www.ncbi.nlm.nih.gov/pubmed/20683 |

Meladrazine is a drug used in urology as an antispasmodic. Meladrazine acts on the central nervous system as a polysynaptic inhibitor. Its usefulness in treating spasticity in patients with multiple sclerosis is well known. As many of these patients have bladder problems, a coincidental beneficial effect on uninhibited bladders has been discovered. Meladrazine caused a high incidence of side effects; therefore, treatment with terodiline separately is recommended for geriatric patients who have severe motor urge incontinence.

Approval Year

PubMed

PubMed

Title	Date	PubMed
N,N,N,N-Tetra-ethyl-6-{2-[(E)-1-(4-nitro-phen-yl)ethyl-idene]hydrazino}-1,3,5-triazine-2,4-diamine.	2009 Jul 11	21583544

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:23:29 UTC 2023` Edited by `admin` on `Fri Dec 15 16:23:29 UTC 2023`
Record UNII	2V6Z0JG2X0
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MELADRAZINE

Official Name

English

meladrazine [INN]

Common Name

English

Meladrazine [WHO-DD]

Common Name

English

2,4-BIS(DIETHYLAMINO)-6-HYDRAZINO-S-TRIAZINE

Systematic Name

English

BA 13155 FREE BASE

Code

English

HYDRAMITRAZINE [MI]

Common Name

English

NSC-99857

Code

English

BA-13155 FREE BASE

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29698

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

WHO-VATC

QG04BD03

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

WHO-ATC

G04BD03

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

Code System Code Type Description

FDA UNII

2V6Z0JG2X0

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

PRIMARY

EPA CompTox

DTXSID20161107

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

PRIMARY

PUBCHEM

71679

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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NSC

99857

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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SMS_ID

100000081444

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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DRUG BANK

DB13272

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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DRUG CENTRAL

3756

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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ECHA (EC/EINECS)

237-736-9

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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WIKIPEDIA

MELADRAZINE

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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MERCK INDEX

m238

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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Merck Index

CAS

13957-36-3

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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NCI_THESAURUS

C66076

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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EVMPD

SUB08717MIG

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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INN

1798

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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MESH

C005040

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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ChEMBL

CHEMBL2105242

Created by admin on Fri Dec 15 16:23:29 UTC 2023 , Edited by admin on Fri Dec 15 16:23:29 UTC 2023

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Related Record Type Details


					7F3DYQ3H7H

MELADRAZINE TARTRATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					2V6Z0JG2X0

ACTIVE MOIETY