MELADRAZINE TARTRATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C11H23N7.C4H6O6
Molecular Weight	403.4341
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CCN(CC)C1=NC(=N\C(N1)=N\N)N(CC)CC

InChI

InChIKey=VYNYHQSBWOQQSB-LREBCSMRSA-N

InChI=1S/C11H23N7.C4H6O6/c1-5-17(6-2)10-13-9(16-12)14-11(15-10)18(7-3)8-4;5-1(3(7)8)2(6)4(9)10/h5-8,12H2,1-4H3,(H,13,14,15,16);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1

HIDE SMILES / InChI

Molecular Formula	C4H6O6
Molecular Weight	150.0868
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	C11H23N7
Molecular Weight	253.3472
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3880780 | https://www.ncbi.nlm.nih.gov/pubmed/19160231 | https://www.ncbi.nlm.nih.gov/pubmed/20683 |

Meladrazine is a drug used in urology as an antispasmodic. Meladrazine acts on the central nervous system as a polysynaptic inhibitor. Its usefulness in treating spasticity in patients with multiple sclerosis is well known. As many of these patients have bladder problems, a coincidental beneficial effect on uninhibited bladders has been discovered. Meladrazine caused a high incidence of side effects; therefore, treatment with terodiline separately is recommended for geriatric patients who have severe motor urge incontinence.

Approval Year

PubMed

Title	Date	PubMed
N,N,N,N-Tetra-ethyl-6-{2-[(E)-1-(4-nitro-phen-yl)ethyl-idene]hydrazino}-1,3,5-triazine-2,4-diamine.	2009 Jul 11	21583544

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:54:40 UTC 2023` Edited by `admin` on `Sat Dec 16 05:54:40 UTC 2023`
Record UNII	7F3DYQ3H7H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MELADRAZINE TARTRATE

Common Name

English

1,3,5-TRIAZIN-2(1H)-ONE, 4,6-BIS(DIETHYLAMINO)-, HYDRAZONE, (R-(R*,R*))-2,3-DIHYDROXYBUTANEDIOATE (1:1)

Systematic Name

English

HYDRAMITRAZINE D-TARTRATE [MI]

Common Name

English

HYDRAMITRAZINE TARTRATE

Common Name

English

Meladrazine tartrate [WHO-DD]

Common Name

English

S-TRIAZINE, 2,4-BIS(ETHYLAMINO)-6-HYDRAZINO-, (+)-TARTRATE (1:1)

Systematic Name

English

BA-13155 TARTRATE

Code

English

LISIDONIL

Brand Name

English

BA-13155

Code

English

1,3,5-TRIAZIN-2(1H)-ONE, 4,6-BIS(DIETHYLAMINO)-, HYDRAZONE, (2R,3R)-2,3-DIHYDROXYBUTANEDIOATE (1:1)

Systematic Name

English

BA 13155

Code

English

Code System Code Type Description

CAS

20423-87-4