GUANACLINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H18N4
Molecular Weight	182.266
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of GUANACLINE

Structure Search

SMILES

CC1=CCN(CCNC(N)=N)CC1

InChI

InChIKey=WQVAYGCXSJMPRT-UHFFFAOYSA-N

InChI=1S/C9H18N4/c1-8-2-5-13(6-3-8)7-4-12-9(10)11/h2H,3-7H2,1H3,(H4,10,11,12)

HIDE SMILES / InChI

Molecular Formula	C9H18N4
Molecular Weight	182.266
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5420832

Guanacline was studied in the treatment of hypertension. However, information about the current use of this compound is not available.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Guanacline, a new hypotensive drug.	1969 Jan 25	5779041
Clinical experiences with Leron (guanacline) in the treatment of hypertension.	1970 May 9	5420832
Species and structural specificity of the lipopigment accumulation and neuronal destruction induced by N-(2-guanidinoethyl)-4-methyl-1,2,5,6-tetrahydropyridine (guanacline).	1986 Sep 24	3768685

Substance Class	Chemical Created by `admin` on `Fri Dec 15 14:59:05 UTC 2023` Edited by `admin` on `Fri Dec 15 14:59:05 UTC 2023`
Record UNII	2S93M1DW13
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GUANACLINE

Official Name

English

guanacline [INN]

Common Name

English

(2-(3,6-DIHYDRO-4-METHYL-1(2H)-PYRIDYL)ETHYL)GUANIDINE

Systematic Name

English

GUANIDINE, (2-(3,6-DIHYDRO-4-METHYL-1(2H)-PYRIDINYL)ETHYL)-

Systematic Name

English

GUANACLINE [MI]

Common Name

English

Guanacline [WHO-DD]

Common Name

English

Code System Code Type Description

MERCK INDEX

m221

Created by admin on Fri Dec 15 14:59:05 UTC 2023 , Edited by admin on Fri Dec 15 14:59:05 UTC 2023

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Merck Index

EVMPD

SUB07979MIG

Created by admin on Fri Dec 15 14:59:05 UTC 2023 , Edited by admin on Fri Dec 15 14:59:05 UTC 2023

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MESH

C004943

Created by admin on Fri Dec 15 14:59:05 UTC 2023 , Edited by admin on Fri Dec 15 14:59:05 UTC 2023

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NCI_THESAURUS

C166589

Created by admin on Fri Dec 15 14:59:05 UTC 2023 , Edited by admin on Fri Dec 15 14:59:05 UTC 2023

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PUBCHEM

15102

Created by admin on Fri Dec 15 14:59:05 UTC 2023 , Edited by admin on Fri Dec 15 14:59:05 UTC 2023

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FDA UNII

2S93M1DW13

Created by admin on Fri Dec 15 14:59:05 UTC 2023 , Edited by admin on Fri Dec 15 14:59:05 UTC 2023

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SMS_ID

100000084451

Created by admin on Fri Dec 15 14:59:05 UTC 2023 , Edited by admin on Fri Dec 15 14:59:05 UTC 2023

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CAS

1463-28-1

Created by admin on Fri Dec 15 14:59:05 UTC 2023 , Edited by admin on Fri Dec 15 14:59:05 UTC 2023

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ChEMBL

CHEMBL1160385

Created by admin on Fri Dec 15 14:59:05 UTC 2023 , Edited by admin on Fri Dec 15 14:59:05 UTC 2023

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INN

2150

Created by admin on Fri Dec 15 14:59:05 UTC 2023 , Edited by admin on Fri Dec 15 14:59:05 UTC 2023

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EPA CompTox

DTXSID90163350

Created by admin on Fri Dec 15 14:59:05 UTC 2023 , Edited by admin on Fri Dec 15 14:59:05 UTC 2023

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DRUG CENTRAL

3454

Created by admin on Fri Dec 15 14:59:05 UTC 2023 , Edited by admin on Fri Dec 15 14:59:05 UTC 2023

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					2S93M1DW13

ACTIVE MOIETY