GUANACLINE SULFATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H18N4.2H2O.H2O4S
Molecular Weight	316.375
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O.O.OS(O)(=O)=O.CC1=CCN(CCNC(N)=N)CC1

InChI

InChIKey=RCWLESWTVSJYOL-UHFFFAOYSA-N

InChI=1S/C9H18N4.H2O4S.2H2O/c1-8-2-5-13(6-3-8)7-4-12-9(10)11;1-5(2,3)4;;/h2H,3-7H2,1H3,(H4,10,11,12);(H2,1,2,3,4);2*1H2

HIDE SMILES / InChI

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C9H18N4
Molecular Weight	182.266
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H2O4S
Molecular Weight	98.078
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5420832

Guanacline was studied in the treatment of hypertension. However, information about the current use of this compound is not available.

Approval Year

PubMed

Title	Date	PubMed
Species and structural specificity of the lipopigment accumulation and neuronal destruction induced by N-(2-guanidinoethyl)-4-methyl-1,2,5,6-tetrahydropyridine (guanacline).	1986-09-24	3768685
Clinical experiences with Leron (guanacline) in the treatment of hypertension.	1970-05-09	5420832
Guanacline, a new hypotensive drug.	1969-01-25	5779041

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:52:49 GMT 2025` Edited by `admin` on `Mon Mar 31 17:52:49 GMT 2025`
Record UNII	53U17IG4X9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

B -1464

Preferred Name

English

GUANACLINE SULFATE

Official Name

English

GUANIDINE, (2-(3,6-DIHYDRO-4-METHYL-1(2H)-PYRIDINYL)ETHYL)-, SULFATE (1:1), DIHYDRATE

Common Name

English

GUANACLINE SULFATE [USAN]

Common Name

English

GUANACLINE SULPHATE

Common Name

English

GUANIDINE, (2-(3,6-DIHYDRO-4-METHYL-1(2H)-PYRIDINYL)ETHYL)-, SULPHATE (1:1), DIHYDRATE

Common Name

English

[2-(3,6-Dihydro-4-methyl-1(2H)-pyridyl)ethyl]guanidine sulfate (1:1) dihydrate

Common Name

English

B-1464

Code

English

(2-(3,6-DIHYDRO-4-METHYL-1(2H)-PYRIDYL)ETHYL)GUANIDINE SULPHATE (1:1) DIHYDRATE

Common Name

English

Guanacline sulfate [WHO-DD]

Common Name

English

B 1464

Code

English

Code System Code Type Description

ChEMBL

CHEMBL1160385