Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C25H26F2N6OS |
| Molecular Weight | 496.575 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(CSC1=NC=NC2=C1N=CN2)CN3CCN(CC3)C(C4=CC=C(F)C=C4)C5=CC=C(F)C=C5
InChI
InChIKey=JOMBZLFCXNSKEQ-UHFFFAOYSA-N
InChI=1S/C25H26F2N6OS/c26-19-5-1-17(2-6-19)23(18-3-7-20(27)8-4-18)33-11-9-32(10-12-33)13-21(34)14-35-25-22-24(29-15-28-22)30-16-31-25/h1-8,15-16,21,23,34H,9-14H2,(H,28,29,30,31)
| Molecular Formula | C25H26F2N6OS |
| Molecular Weight | 496.575 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Carsatrin (also known as RWJ 24517) is purinylpiperazine derivative patented by Ortho Pharmaceutical Corp. as cardiotonic and antiarrhythmic. Carsatrin acts as positive inotropic agent that increases twitch tension and prolongs the action potential (AP) duration of ventricular muscle without affecting the Na+,K+-ATPase, adenylyl cyclase, phosphodiesterase isozymes, or cardiac myofilaments. Carsatrin’s positive inotropic effect can be prevented by tetrodotoxin but not by the adrenergic antagonists timolol, yohimbine, or prazosin
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 18:03:10 GMT 2023
by
admin
on
Sat Dec 16 18:03:10 GMT 2023
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| Record UNII |
2E3S34L69I
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Systematic Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C78322
Created by
admin on Sat Dec 16 18:03:11 GMT 2023 , Edited by admin on Sat Dec 16 18:03:11 GMT 2023
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| Code System | Code | Type | Description | ||
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125363-87-3
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SUB06147MIG
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DTXSID90869724
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100000081348
Created by
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C078816
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193951
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CHEMBL313458
Created by
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6975
Created by
admin on Sat Dec 16 18:03:11 GMT 2023 , Edited by admin on Sat Dec 16 18:03:11 GMT 2023
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2E3S34L69I
Created by
admin on Sat Dec 16 18:03:11 GMT 2023 , Edited by admin on Sat Dec 16 18:03:11 GMT 2023
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PRIMARY | |||
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C79875
Created by
admin on Sat Dec 16 18:03:11 GMT 2023 , Edited by admin on Sat Dec 16 18:03:11 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ENANTIOMER -> RACEMATE | |||
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SALT/SOLVATE -> PARENT | |||
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ENANTIOMER -> RACEMATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
