Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C25H26F2N6OS.C4H6O4 |
| Molecular Weight | 614.663 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CCC(O)=O.OC(CSC1=C2N=CN=C2N=CN1)CN3CCN(CC3)C(C4=CC=C(F)C=C4)C5=CC=C(F)C=C5
InChI
InChIKey=HITUQCDKZKCYIZ-UHFFFAOYSA-N
InChI=1S/C25H26F2N6OS.C4H6O4/c26-19-5-1-17(2-6-19)23(18-3-7-20(27)8-4-18)33-11-9-32(10-12-33)13-21(34)14-35-25-22-24(29-15-28-22)30-16-31-25;5-3(6)1-2-4(7)8/h1-8,15-16,21,23,34H,9-14H2,(H,28,29,30,31);1-2H2,(H,5,6)(H,7,8)
| Molecular Formula | C4H6O4 |
| Molecular Weight | 118.088 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C25H26F2N6OS |
| Molecular Weight | 496.575 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Carsatrin (also known as RWJ 24517) is purinylpiperazine derivative patented by Ortho Pharmaceutical Corp. as cardiotonic and antiarrhythmic. Carsatrin acts as positive inotropic agent that increases twitch tension and prolongs the action potential (AP) duration of ventricular muscle without affecting the Na+,K+-ATPase, adenylyl cyclase, phosphodiesterase isozymes, or cardiac myofilaments. Carsatrin’s positive inotropic effect can be prevented by tetrodotoxin but not by the adrenergic antagonists timolol, yohimbine, or prazosin
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:32:52 GMT 2023
by
admin
on
Fri Dec 15 16:32:52 GMT 2023
|
| Record UNII |
YAZ544QOFD
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Code | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C78322
Created by
admin on Fri Dec 15 16:32:52 GMT 2023 , Edited by admin on Fri Dec 15 16:32:52 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
132199-13-4
Created by
admin on Fri Dec 15 16:32:52 GMT 2023 , Edited by admin on Fri Dec 15 16:32:52 GMT 2023
|
PRIMARY | |||
|
YAZ544QOFD
Created by
admin on Fri Dec 15 16:32:52 GMT 2023 , Edited by admin on Fri Dec 15 16:32:52 GMT 2023
|
PRIMARY | |||
|
CHEMBL313458
Created by
admin on Fri Dec 15 16:32:52 GMT 2023 , Edited by admin on Fri Dec 15 16:32:52 GMT 2023
|
PRIMARY | |||
|
C76029
Created by
admin on Fri Dec 15 16:32:52 GMT 2023 , Edited by admin on Fri Dec 15 16:32:52 GMT 2023
|
PRIMARY | |||
|
DD-61
Created by
admin on Fri Dec 15 16:32:52 GMT 2023 , Edited by admin on Fri Dec 15 16:32:52 GMT 2023
|
PRIMARY | |||
|
193950
Created by
admin on Fri Dec 15 16:32:52 GMT 2023 , Edited by admin on Fri Dec 15 16:32:52 GMT 2023
|
PRIMARY | |||
|
DTXSID70927578
Created by
admin on Fri Dec 15 16:32:52 GMT 2023 , Edited by admin on Fri Dec 15 16:32:52 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
PARENT -> SALT/SOLVATE | |||
|
|
ENANTIOMER -> RACEMATE | |||
|
|
ENANTIOMER -> RACEMATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |