Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H14FN5OS |
| Molecular Weight | 367.4 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@]1(C=CSC(N)=N1)C2=CC(NC(=O)C3=NC=C(C=C3)C#N)=CC=C2F
InChI
InChIKey=VLLFGVHGKLDDLW-SFHVURJKSA-N
InChI=1S/C18H14FN5OS/c1-18(6-7-26-17(21)24-18)13-8-12(3-4-14(13)19)23-16(25)15-5-2-11(9-20)10-22-15/h2-8,10H,1H3,(H2,21,24)(H,23,25)/t18-/m0/s1
| Molecular Formula | C18H14FN5OS |
| Molecular Weight | 367.4 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
Cmax
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
6.72 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
1 mg single, oral dose: 1 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
5.62 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
1 mg single, oral dose: 1 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
17.2 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
3 mg single, oral dose: 3 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
83.9 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
10 mg single, oral dose: 10 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
148 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg single, oral dose: 30 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
519 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg single, oral dose: 90 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
906 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
150 mg single, oral dose: 150 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
2.94 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
10 mg single, oral dose: 10 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
6.34 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg single, oral dose: 30 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
17.6 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg single, oral dose: 90 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
22.7 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
150 mg single, oral dose: 150 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
202 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg 1 times / day steady-state, oral dose: 30 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
791 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg 1 times / day steady-state, oral dose: 90 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
1210 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
150 mg 1 times / day steady-state, oral dose: 150 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
23.5 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
5 mg single, oral dose: 5 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
171 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
25 mg single, oral dose: 25 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
279 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
50 mg single, oral dose: 50 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
38.7 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
5 mg 1 times / day steady-state, oral dose: 5 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
210 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
25 mg 1 times / day steady-state, oral dose: 25 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
202 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg 1 times / day steady-state, oral dose: 30 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
364 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
50 mg 1 times / day steady-state, oral dose: 50 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
699 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg 1 times / day steady-state, oral dose: 90 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
1.54 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
5 mg 1 times / day multiple, oral dose: 5 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
6.42 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
25 mg 1 times / day multiple, oral dose: 25 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
8.14 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg 1 times / day multiple, oral dose: 30 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
14.5 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
50 mg 1 times / day multiple, oral dose: 50 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
21.9 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg 1 times / day multiple, oral dose: 90 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
AUC
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
64.7 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
1 mg single, oral dose: 1 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
57.5 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
1 mg single, oral dose: 1 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
232 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
3 mg single, oral dose: 3 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
948 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
10 mg single, oral dose: 10 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
2253 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg single, oral dose: 30 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
7822 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg single, oral dose: 90 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
12730 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
150 mg single, oral dose: 150 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
21.4 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
10 mg single, oral dose: 10 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
63.2 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg single, oral dose: 30 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
233 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg single, oral dose: 90 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
358 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
150 mg single, oral dose: 150 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
2717 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg 1 times / day steady-state, oral dose: 30 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
10347 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg 1 times / day steady-state, oral dose: 90 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
13518 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
150 mg 1 times / day steady-state, oral dose: 150 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
285 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
5 mg single, oral dose: 5 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
1681 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
25 mg single, oral dose: 25 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
3323 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
50 mg single, oral dose: 50 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
548 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
5 mg 1 times / day steady-state, oral dose: 5 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
2727 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
25 mg 1 times / day steady-state, oral dose: 25 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
2897 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg 1 times / day steady-state, oral dose: 30 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
5509 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
50 mg 1 times / day steady-state, oral dose: 50 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
9294 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg 1 times / day steady-state, oral dose: 90 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
89.2 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
25 mg 1 times / day multiple, oral dose: 25 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
119 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg 1 times / day multiple, oral dose: 30 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
202 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
50 mg 1 times / day multiple, oral dose: 50 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
308 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg 1 times / day multiple, oral dose: 90 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
T1/2
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
9 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
1 mg single, oral dose: 1 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
11.7 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
1 mg single, oral dose: 1 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
13.9 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
3 mg single, oral dose: 3 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
14.4 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
10 mg single, oral dose: 10 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
15.7 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg single, oral dose: 30 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
16.1 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg single, oral dose: 90 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
15.1 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
150 mg single, oral dose: 150 mg route of administration: Oral experiment type: SINGLE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
17 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
5 mg 1 times / day steady-state, oral dose: 5 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
15.8 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
25 mg 1 times / day steady-state, oral dose: 25 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
17.2 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg 1 times / day steady-state, oral dose: 30 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
18.5 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
50 mg 1 times / day steady-state, oral dose: 50 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
14.4 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg 1 times / day steady-state, oral dose: 90 mg route of administration: Oral experiment type: STEADY-STATE co-administered: |
ATABECESTAT plasma | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
13.6 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
25 mg 1 times / day multiple, oral dose: 25 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
13.9 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
30 mg 1 times / day multiple, oral dose: 30 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
14.4 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
50 mg 1 times / day multiple, oral dose: 50 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
|
11.7 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/29067308/ |
90 mg 1 times / day multiple, oral dose: 90 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
ATABECESTAT cerebrospinal fluid | Homo sapiens population: HEALTHY age: ADULT sex: FEMALE / MALE food status: FASTED |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:26:58 GMT 2025
by
admin
on
Mon Mar 31 23:26:58 GMT 2025
|
| Record UNII |
2834W8D6GK
|
| Record Status |
Validated (UNII)
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| Record Version |
|
-
Download
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Official Name | English | ||
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Preferred Name | English | ||
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Systematic Name | English | ||
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Code | English | ||
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Code | English |
| Code System | Code | Type | Description | ||
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C166553
Created by
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DB15307
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admin on Mon Mar 31 23:26:58 GMT 2025 , Edited by admin on Mon Mar 31 23:26:58 GMT 2025
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68254185
Created by
admin on Mon Mar 31 23:26:58 GMT 2025 , Edited by admin on Mon Mar 31 23:26:58 GMT 2025
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10650
Created by
admin on Mon Mar 31 23:26:58 GMT 2025 , Edited by admin on Mon Mar 31 23:26:58 GMT 2025
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2834W8D6GK
Created by
admin on Mon Mar 31 23:26:58 GMT 2025 , Edited by admin on Mon Mar 31 23:26:58 GMT 2025
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FG-54
Created by
admin on Mon Mar 31 23:26:58 GMT 2025 , Edited by admin on Mon Mar 31 23:26:58 GMT 2025
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100000177913
Created by
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1972652-51-9
Created by
admin on Mon Mar 31 23:26:58 GMT 2025 , Edited by admin on Mon Mar 31 23:26:58 GMT 2025
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NO STRUCTURE GIVEN | |||
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1200493-78-2
Created by
admin on Mon Mar 31 23:26:58 GMT 2025 , Edited by admin on Mon Mar 31 23:26:58 GMT 2025
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PRIMARY |
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TARGET -> INHIBITOR |
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ACTIVE MOIETY |
