Details
Stereochemistry | ACHIRAL |
Molecular Formula | C27H22F4N4O3S.ClH.H2O |
Molecular Weight | 613.023 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
O.Cl.FC1=CC=C(C=C1)S(=O)(=O)N2CCN(CC2)C(=O)C3=CC=C(NC4=C5C=CC(=CC5=NC=C4)C(F)(F)F)C=C3
InChI
InChIKey=FLWHGDVIICGHDP-UHFFFAOYSA-N
InChI=1S/C27H22F4N4O3S.ClH.H2O/c28-20-4-8-22(9-5-20)39(37,38)35-15-13-34(14-16-35)26(36)18-1-6-21(7-2-18)33-24-11-12-32-25-17-19(27(29,30)31)3-10-23(24)25;;/h1-12,17H,13-16H2,(H,32,33);1H;1H2
Molecular Formula | H2O |
Molecular Weight | 18.0153 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C27H22F4N4O3S |
Molecular Weight | 558.547 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Losulazine (U-54,669F) is an antihypertensive agent acting by a sympatholytic mechanism. It appears to alter peripheral sympathetic neurogenic function but apparently does not enter the central nervous system. Losulazine effectively lowered the blood pressure in patients with hypertension.
Originator
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:02:52 GMT 2023
by
admin
on
Fri Dec 15 15:02:52 GMT 2023
|
Record UNII |
267UX099PD
|
Record Status |
Validated (UNII)
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Record Version |
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-
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Common Name | English |
Code System | Code | Type | Description | ||
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6917756
Created by
admin on Fri Dec 15 15:02:52 GMT 2023 , Edited by admin on Fri Dec 15 15:02:52 GMT 2023
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PRIMARY | |||
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267UX099PD
Created by
admin on Fri Dec 15 15:02:52 GMT 2023 , Edited by admin on Fri Dec 15 15:02:52 GMT 2023
|
PRIMARY |
Related Record | Type | Details | ||
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ANHYDROUS->SOLVATE | |||
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PARENT -> SALT/SOLVATE |
Related Record | Type | Details | ||
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ACTIVE MOIETY |