Stereochemistry | ACHIRAL |
Molecular Formula | C25H22N4O8 |
Molecular Weight | 506.4642 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C(OC)C(O)=C(C=C1)C2=C(C)C(=NC(C3=NC4=C(C=C3)C(=O)C(OC)=C(N)C4=O)=C2N)C(O)=O
InChI
InChIKey=PVYJZLYGTZKPJE-UHFFFAOYSA-N
InChI=1S/C25H22N4O8/c1-9-14(10-6-8-13(35-2)23(36-3)20(10)30)15(26)19(29-17(9)25(33)34)12-7-5-11-18(28-12)22(32)16(27)24(37-4)21(11)31/h5-8,30H,26-27H2,1-4H3,(H,33,34)
Molecular Formula | C25H22N4O8 |
Molecular Weight | 506.4642 |
Charge | 0 |
Count |
MOL RATIO
1 MOL RATIO (average) |
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Streptonigrin is an antibiotic produced by Streptomyces flocculus. Streptonigrin exhibits activity as a broad spectrum antibiotic against both Gram-positive and Gram-negative bacteria. Streptonigrin shows antitumor activity against sarcomas, carcinomas, leukemias and lymphomas in vivo and in vitro. Due to its high toxicity, streptonigrin has not recieved widespread clinical use.
Originator
Approval Year
Sourcing
PubMed
Patents
Sample Use Guides
In clinical trials, streptonigrin was administered by intravenous infusion (daily dose 7 ug/kg), or orally in the form of 0.2 mg capsule.
Route of Administration:
Other