DIETHANOLAMINE FUSIDATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C31H48O6.C4H11NO2
Molecular Weight	621.8449
Optical Activity	UNSPECIFIED
Defined Stereocenters	10 / 10
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OCCNCCO.[H][C@@]12C[C@@H](O)[C@@]3([H])[C@@]4(C)CC[C@@H](O)[C@@H](C)[C@]4([H])CC[C@]3(C)[C@@]1(C)C[C@H](OC(C)=O)\C2=C(\CCC=C(C)C)C(O)=O

InChI

InChIKey=OQZZCXRLEFBPLZ-JCJNLNMISA-N

InChI=1S/C31H48O6.C4H11NO2/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;6-3-1-5-2-4-7/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);5-7H,1-4H2/b26-20-;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1

HIDE SMILES / InChI

Molecular Formula	C31H48O6
Molecular Weight	516.7092
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	10 / 10
E/Z Centers	1
Optical Activity	UNSPECIFIED

Molecular Formula	C4H11NO2
Molecular Weight	105.1356
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Marked in vivo antiretrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine, a selective anti-human immunodeficiency virus agent.	1989 Jan	2911579
Suppression of HIV replication in vitro by fusidic acid parallels cell toxicity.	1989 Jan	2745249
Bacteremia and infective endocarditis caused by a non-daptomycin-susceptible, vancomycin-intermediate, and methicillin-resistant Staphylococcus aureus strain in Taiwan.	2008 Mar	18199793
Severe statin-induced rhabdomyolysis mimicking Guillain-Barré syndrome in four patients with diabetes mellitus treated with fusidic acid.	2010 Jun	20546290
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.	2013 Nov	23956101
A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.	2014 Jan	24085192

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 20:31:41 GMT 2023` Edited by `admin` on `Fri Dec 15 20:31:41 GMT 2023`
Record UNII	1XKK7J9CT6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIETHANOLAMINE FUSIDATE

Common Name

English

FUSIDATE DIOLAMINE

Common Name

English

29-NORDAMMARA-17(20),24-DIEN-21-OIC ACID, 16-(ACETYLOXY)-3,11-DIHYDROXY-, (3.ALPHA.,4.ALPHA.,8.ALPHA.,9.ALPHA.,11.ALPHA.,13.ALPHA.,14.BETA.,16.BETA.,17Z)-, COMPD. WITH 2,2'-IMINOBIS(ETHANOL) (1:1)

Common Name

English

FUSIDATE DIETHANOLAMINE

Common Name

English

Diethanolamine fusidate [WHO-DD]

Common Name

English

Code System Code Type Description

SMS_ID

100000079554