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Details

Stereochemistry ABSOLUTE
Molecular Formula C31H48O6.C4H11NO2
Molecular Weight 621.8449
Optical Activity UNSPECIFIED
Defined Stereocenters 10 / 10
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of DIETHANOLAMINE FUSIDATE

SMILES

OCCNCCO.[H][C@@]12C[C@@H](O)[C@@]3([H])[C@@]4(C)CC[C@@H](O)[C@@H](C)[C@]4([H])CC[C@]3(C)[C@@]1(C)C[C@H](OC(C)=O)\C2=C(\CCC=C(C)C)C(O)=O

InChI

InChIKey=OQZZCXRLEFBPLZ-JCJNLNMISA-N
InChI=1S/C31H48O6.C4H11NO2/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;6-3-1-5-2-4-7/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);5-7H,1-4H2/b26-20-;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1

HIDE SMILES / InChI

Molecular Formula C31H48O6
Molecular Weight 516.7092
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 10 / 10
E/Z Centers 1
Optical Activity UNSPECIFIED

Molecular Formula C4H11NO2
Molecular Weight 105.1356
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Haematuria during methicillin therapy.
1971 Jul
Protein synthesis in Mycobacterium tuberculosis H37Rv and the effect of streptomycin in streptomycin-susceptible and -resistant strains.
1973 Sep
Screening for new compounds with antiherpes activity.
1984 Oct
Fusidic acid-induced hyperbilirubinemia.
1987 Aug
Inhibition of HIV replication in vitro by fusidic acid.
1987 Oct 10
Suppression of HIV replication in vitro by fusidic acid parallels cell toxicity.
1989 Jan
Acute renal failure in association with fusidic acid.
1997 Jun
In vitro susceptibility of Mycobacterium tuberculosis to fusidic acid.
2001 Dec
Hypocalcaemia during fusidic acid therapy.
2002 Feb
[Cholestatic icterus induced by the administration of fusidic acid in a cirrhotic patient].
2002 Jun 29
Sideroblastic anaemia and fusidic acid.
2003 Feb
Sideroblastic anaemia during fusidic acid treatment.
2004 May
Linezolid for the treatment of patients with endocarditis: a systematic review of the published evidence.
2006 Aug
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
2010 Dec
Severe statin-induced rhabdomyolysis mimicking Guillain-Barré syndrome in four patients with diabetes mellitus treated with fusidic acid.
2010 Jun
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
2013 Nov
A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.
2014 Jan
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 20:31:41 GMT 2023
Edited
by admin
on Fri Dec 15 20:31:41 GMT 2023
Record UNII
1XKK7J9CT6
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIETHANOLAMINE FUSIDATE
WHO-DD  
Common Name English
FUSIDATE DIOLAMINE
Common Name English
29-NORDAMMARA-17(20),24-DIEN-21-OIC ACID, 16-(ACETYLOXY)-3,11-DIHYDROXY-, (3.ALPHA.,4.ALPHA.,8.ALPHA.,9.ALPHA.,11.ALPHA.,13.ALPHA.,14.BETA.,16.BETA.,17Z)-, COMPD. WITH 2,2'-IMINOBIS(ETHANOL) (1:1)
Common Name English
FUSIDATE DIETHANOLAMINE
Common Name English
Diethanolamine fusidate [WHO-DD]
Common Name English
Code System Code Type Description
SMS_ID
100000079554
Created by admin on Fri Dec 15 20:31:41 GMT 2023 , Edited by admin on Fri Dec 15 20:31:41 GMT 2023
PRIMARY
FDA UNII
1XKK7J9CT6
Created by admin on Fri Dec 15 20:31:41 GMT 2023 , Edited by admin on Fri Dec 15 20:31:41 GMT 2023
PRIMARY
ECHA (EC/EINECS)
240-442-3
Created by admin on Fri Dec 15 20:31:41 GMT 2023 , Edited by admin on Fri Dec 15 20:31:41 GMT 2023
PRIMARY
EVMPD
SUB13572MIG
Created by admin on Fri Dec 15 20:31:41 GMT 2023 , Edited by admin on Fri Dec 15 20:31:41 GMT 2023
PRIMARY
MESH
C013483
Created by admin on Fri Dec 15 20:31:41 GMT 2023 , Edited by admin on Fri Dec 15 20:31:41 GMT 2023
PRIMARY
CAS
16391-75-6
Created by admin on Fri Dec 15 20:31:41 GMT 2023 , Edited by admin on Fri Dec 15 20:31:41 GMT 2023
PRIMARY
PUBCHEM
46174083
Created by admin on Fri Dec 15 20:31:41 GMT 2023 , Edited by admin on Fri Dec 15 20:31:41 GMT 2023
PRIMARY
EPA CompTox
DTXSID701020012
Created by admin on Fri Dec 15 20:31:41 GMT 2023 , Edited by admin on Fri Dec 15 20:31:41 GMT 2023
PRIMARY
RXCUI
22971
Created by admin on Fri Dec 15 20:31:41 GMT 2023 , Edited by admin on Fri Dec 15 20:31:41 GMT 2023
PRIMARY RxNorm
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE