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Details

Stereochemistry ABSOLUTE
Molecular Formula C24H30NO4
Molecular Weight 396.4993
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 1

SHOW SMILES / InChI
Structure of TROPENZILINE

SMILES

CO[C@@H]1C[C@H]2C[C@H](C[C@@H]1[N+]2(C)C)OC(=O)C(O)(C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChIKey=UOGRTPHUCQXAJU-YUMYIRISSA-N
InChI=1S/C24H30NO4/c1-25(2)19-14-20(16-21(25)22(15-19)28-3)29-23(26)24(27,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-13,19-22,27H,14-16H2,1-3H3/q+1/t19-,20-,21+,22-/m1/s1

HIDE SMILES / InChI

Molecular Formula C24H30NO4
Molecular Weight 396.4993
Charge 1
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Tropenziline is an antispasmodic. It exerted an enhancement of the vasoconstrictor responses of hepatic artery to low concentrations of adrenaline with no effect on the portal venous bed in the isolated perfused liver of rabbit. Tropenziline interferes with nervous transmission in the vagal plexus of the intestine and thus exerts a spasmolytic effect, which has also been confirmed clinically.

Approval Year

PubMed

PubMed

TitleDatePubMed
The actions of atropine, tropenziline and N-butyl hyoscine bromide on the isolated distal colon of the guinea-pig: a comparison of their activities and mechanisms of action.
1969 Oct
A study of the inhibition of adrenaline-induced vasoconstriction in the isolated perfused liver of rabbit.
1990 Nov
Substance Class Chemical
Created
by admin
on Sat Dec 16 01:19:39 GMT 2023
Edited
by admin
on Sat Dec 16 01:19:39 GMT 2023
Record UNII
1X9E02O59P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TROPENZILINE
WHO-DD  
Common Name English
TROPENZILINE CATION
Common Name English
7-METHOXY-8-METHYLTROPINIUM BENZILATE
Common Name English
8-AZONIABICYCLO(3.2.1)OCTANE, 3-((2-HYDROXY-2,2-DIPHENYLACETYL)OXY)-6-METHOXY-8,8-DIMETHYL-
Systematic Name English
Tropenziline [WHO-DD]
Common Name English
TROPENZILINE ION
Common Name English
Code System Code Type Description
PUBCHEM
71587059
Created by admin on Sat Dec 16 01:19:39 GMT 2023 , Edited by admin on Sat Dec 16 01:19:39 GMT 2023
PRIMARY
FDA UNII
1X9E02O59P
Created by admin on Sat Dec 16 01:19:39 GMT 2023 , Edited by admin on Sat Dec 16 01:19:39 GMT 2023
PRIMARY
CAS
23409-43-0
Created by admin on Sat Dec 16 01:19:39 GMT 2023 , Edited by admin on Sat Dec 16 01:19:39 GMT 2023
PRIMARY
EPA CompTox
DTXSID40177962
Created by admin on Sat Dec 16 01:19:39 GMT 2023 , Edited by admin on Sat Dec 16 01:19:39 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY