TROPENZILINE BROMIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H30NO4.Br
Molecular Weight	476.403
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Br-].CO[C@@H]1C[C@H]2C[C@H](C[C@@H]1[N+]2(C)C)OC(=O)C(O)(C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChIKey=OENFXACOWSBKMV-YGRUNEGGSA-M

InChI=1S/C24H30NO4.BrH/c1-25(2)19-14-20(16-21(25)22(15-19)28-3)29-23(26)24(27,17-10-6-4-7-11-17)18-12-8-5-9-13-18;/h4-13,19-22,27H,14-16H2,1-3H3;1H/q+1;/p-1/t19-,20-,21+,22-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	Br
Molecular Weight	79.904
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C24H30NO4
Molecular Weight	396.4993
Charge	1
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2227814 | https://www.ncbi.nlm.nih.gov/pubmed/4390607

Tropenziline is an antispasmodic. It exerted an enhancement of the vasoconstrictor responses of hepatic artery to low concentrations of adrenaline with no effect on the portal venous bed in the isolated perfused liver of rabbit. Tropenziline interferes with nervous transmission in the vagal plexus of the intestine and thus exerts a spasmolytic effect, which has also been confirmed clinically.

Approval Year

PubMed

Title	Date	PubMed
A study of the inhibition of adrenaline-induced vasoconstriction in the isolated perfused liver of rabbit.	1990-11	2227814
The actions of atropine, tropenziline and N-butyl hyoscine bromide on the isolated distal colon of the guinea-pig: a comparison of their activities and mechanisms of action.	1969-10	4390607

Substance Class	Chemical Created by `admin` on `Wed Apr 02 08:03:54 GMT 2025` Edited by `admin` on `Wed Apr 02 08:03:54 GMT 2025`
Record UNII	MNQ72KR8VM
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PALEROL

Preferred Name

English

TROPENZILINE BROMIDE

Official Name

English

MTS-263

Code

English

TROPENZILIUM BROMIDE

Common Name

English

7-METHOXY-8-METHYLTROPINIUM BROMIDE BENZILATE

Common Name

English

PALEROSAN

Brand Name

English

Tropenziline bromide [WHO-DD]

Common Name

English

TROPENZILE METHYLBROMIDE

Common Name

English

TROPENZILENE BROMIDE

Common Name

English

MTS 263

Code

English

tropenziline bromide [INN]

Common Name

English

TROPENZIL BROMIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29698