Stereochemistry | ACHIRAL |
Molecular Formula | CH2O |
Molecular Weight | 30.026 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
C=O
InChI
InChIKey=WSFSSNUMVMOOMR-UHFFFAOYSA-N
InChI=1S/CH2O/c1-2/h1H2
Molecular Formula | CH2O |
Molecular Weight | 30.026 |
Charge | 0 |
Count |
MOL RATIO
1 MOL RATIO (average) |
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Formaldehyde is a naturally occurring organic compound, and an important industrial precursor to many other materials and organic compounds. Formaldehyde solution (formalin) is used as a disinfectant. Formaldehyde vapors are toxic, upon entry formaldehyde reacts readily with macromolecules, including DNA to form DNA-protein and DNA-DNA cross-links.
CNS Activity
Originator
Approval Year
Sample Use Guides
Formaldehyde 10% solution is applied topically once a day to affected areas.
Route of Administration:
Topical
Human lymphoblasts were exposed in vitro to various concentrations of formaldehyde (HCHO) in single and multiple treatment regimens to determine relative mutagenic efficiency. HCHO treatment resulted in a significant nonlinear increase in DNA-protein crosslinks at concentrations greater than 50 uM X 2 h, which correlated with the onset of significant toxicity in this cell line.