Details
Stereochemistry | ACHIRAL |
Molecular Formula | C2H6N2O |
Molecular Weight | 74.0818 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)N=O
InChI
InChIKey=UMFJAHHVKNCGLG-UHFFFAOYSA-N
InChI=1S/C2H6N2O/c1-4(2)3-5/h1-2H3
Molecular Formula | C2H6N2O |
Molecular Weight | 74.0818 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
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Meat consumption and risk of stomach cancer in Uruguay: a case-control study. | 2001 |
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[Clinico-experimental basis for regional and systemic administration of thiopoietins in liver cirrhosis. Report I]. | 2001 |
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[N-nitrosodimethylamine--toxicologic significance]. | 2001 |
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Chromosome analysis of human spermatozoa following in vitro exposure to cyclophosphamide, benzo(a)pyrene and N-nitrosodimethylamine in the presence of rat liver S9. | 2001 Apr 5 |
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Carbon tetrachloride changes the activity of cytochrome P450 system in the liver of male rats: role of antioxidants. | 2001 Dec 14 |
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Monitoring airborne genotoxicants in the rubber industry using genotoxicity tests and chemical analyses. | 2001 Feb 20 |
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Carcinogenicity assays of wood dust and wood additives in rats exposed by long-term inhalation. | 2001 Mar |
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Alpha-difluoromethylornithine induction of apoptosis: a mechanism which reverses pre-established cell proliferation and cancer initiation in esophageal carcinogenesis in zinc-deficient rats. | 2001 Mar |
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Inhibition of N-nitrosomethylbenzylamine-induced tumorigenesis in the rat esophagus by dietary freeze-dried strawberries. | 2001 Mar |
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Heterogeneity and plasticity of hepatocyte lineage cells. | 2001 Mar |
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The preparation of anthraquinone used in the National Toxicology Program cancer bioassay was contaminated with the mutagen 9-nitroanthracene. | 2001 Mar |
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Gas chromatographic-mass spectrometric determination of hydrophilic compounds in environmental water by solid-phase extraction with activated carbon fiber felt. | 2001 Mar 9 |
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Effects of octreotide on intestinal transit and bacterial translocation in conscious rats with portal hypertension and liver fibrosis. | 2001 Nov |
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Rat oesophageal cytochrome P450 (CYP) monooxygenase system: comparison to the liver and relevance in N-nitrosodiethylamine carcinogenesis. | 2001 Nov |
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S9 induction by the combined treatment with cyclohexanol and albendazole. | 2001 Nov |
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Dimethyl sulfoxide inhibits dimethylnitrosamine-induced hepatic fibrosis in rats. | 2001 Nov |
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TAC-101, a novel retinobenzoic-acid derivative, enhances gap junctional intercellular communication among renal epithelial cells treated with renal carcinogens. | 2001 Nov-Dec |
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N-nitrososdimethylamine is activated in microsomes from hepatocytes to reactive metabolites which damage DNA of non-parenchymal cells in rat liver. | 2001 Sep 15 |
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Preliminary evaluation of the cytotoxic and genotoxic potential of D-003: Mixture of very long chain fatty acids. | 2002 |
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Mechanistic studies of N-nitrosodimethylamine (NDMA) formation in chlorinated drinking water. | 2002 Apr |
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CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism. | 2002 Apr |
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Microsome-mediated oxidation of N-nitrosodiethanolamine (NDELA), a bident carcinogen. | 2002 Apr |
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Decrease in K-ras p21 and increase in Raf1 and activated Erk 1 and 2 in murine lung tumors initiated by N-nitrosodimethylamine and promoted by 2,3,7,8-tetrachlorodibenzo-p-dioxin. | 2002 Feb 15 |
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Structure-activity relationships of several anisidine and dibenzanthracene isomers in the w/w+ somatic assay of Drosophila melanogaster. | 2002 Feb 15 |
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Antimutagenic and anticarcinogenic effects of Phyllanthus amarus. | 2002 Jan |
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DNA adducts and liver DNA replication in rats during chronic exposure to N-nitrosodimethylamine (NDMA) and their relationships to the dose-dependence of NDMA hepatocarcinogenesis. | 2002 Mar 20 |
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Effect of ethanol treatment on metabolic activation and detoxification of esophagus carcinogenic N-nitrosamines in rat liver. | 2002 May |
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Effect of some hypoglycemic herbs on the activity of phase I and II drug-metabolizing enzymes in alloxan-induced diabetic rats. | 2002 May 24 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 17:35:45 GMT 2025
by
admin
on
Mon Mar 31 17:35:45 GMT 2025
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Record UNII |
M43H21IO8R
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Record Status |
Validated (UNII)
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Record Version |
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Classification Tree | Code System | Code | ||
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IARC | <i>N</i>-Nitrosodimethylamine | ||
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NCI_THESAURUS |
C45398
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m7994
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59990
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N-NITROSODIMETHYLAMINE
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1466674
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D004128
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6124
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M43H21IO8R
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35807
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100000183957
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C44417
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62-75-9
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Related Record | Type | Details | ||
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METABOLIC ENZYME -> SUBSTRATE |
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Related Record | Type | Details | ||
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METABOLITE TOXIC -> PARENT |
Formed from breakdown of hydroxymethylmethylnitrosamine can alkylate DNA
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METABOLITE TOXIC -> PARENT |
Activated to methylate DNA
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METABOLITE TOXIC -> PARENT |
Activates N-nitrosoamine to alkylate DNA.
MAJOR
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METABOLITE TOXIC -> PARENT |
Akylating agent
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Related Record | Type | Details | ||
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PARENT -> IMPURITY |
NDMA is an organic chemical that is in a family of potent carcinogens.
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PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is in a family of potent carcinogens.
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PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is in a family of potent carcinogens.
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PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is in a family of potent carcinogens.
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PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is in a family of potent carcinogens.
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PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is part of a family of potent carcinogens.
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PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is in a family of potent carcinogens.
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PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is in a family of potent carcinogens.
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