Details
Stereochemistry | ACHIRAL |
Molecular Formula | C2H6N2O |
Molecular Weight | 74.0818 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)N=O
InChI
InChIKey=UMFJAHHVKNCGLG-UHFFFAOYSA-N
InChI=1S/C2H6N2O/c1-4(2)3-5/h1-2H3
Molecular Formula | C2H6N2O |
Molecular Weight | 74.0818 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
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Promotion of chemically induced rat esophageal tumorigenesis with post-initiation ethanol modification. | 2001 |
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[Morphologic study of renal carcinogenesis in rats induced by dimethylnitrosamine]. | 2001 |
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A selective ROCK inhibitor, Y27632, prevents dimethylnitrosamine-induced hepatic fibrosis in rats. | 2001 Apr |
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Changes in the expression of cytochrome P450 2E1 and the activity of carcinogen-metabolizing enzymes in Schistosoma haematobium-infected human bladder tissues. | 2001 Apr 12 |
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Attempt to adsorb N-nitrosamines in solution by use of zeolites. | 2001 Aug |
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Interactions between methylating and pyridyloxobutylating agents in A/J mouse lungs: implications for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis. | 2001 Aug 1 |
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The influence of very low doses of N-nitrosodimethylamine (NDMA) on the apoptosis of rat neutrophils in vivo. The role of reactive oxygen species. | 2001 Aug 13 |
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Mixture of N-carbamoyl-L-glutamate plus L-arginine can protect rats with liver cirrhosis from acute ammonia intoxication. | 2001 Dec |
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Involvement of reactive oxygen species and nitric oxide radicals in activation and proliferation of rat hepatic stellate cells. | 2001 Feb |
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Dimethylnitrosamine-induced liver injury in rats: the early deposition of collagen. | 2001 Jan 2 |
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2-(Allylthio)pyrazine, a cancer chemopreventive agent, inhibits liver fibrosis induced by dimethylnitrosamine in rats: role of inhibition of transforming growth factor-beta1 expression. | 2001 Jul |
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Pirfenidone inhibits dimethylnitrosamine-induced hepatic fibrosis in rats. | 2001 Jul |
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Effects of dietary N-(4-hydroxyphenyl)retinamide on N-nitrosomethylbenzylamine metabolism and esophageal tumorigenesis in the Fischer 344 rat. | 2001 Jul 4 |
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Importance of DNA repair in carcinogenesis: evidence from transgenic and gene targeting studies. | 2001 Jun 2 |
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Reporter gene transgenic mice as a tool for analyzing the molecular mechanisms underlying experimental carcinogenesis. | 2001 Mar |
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Alpha-difluoromethylornithine induction of apoptosis: a mechanism which reverses pre-established cell proliferation and cancer initiation in esophageal carcinogenesis in zinc-deficient rats. | 2001 Mar |
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Heterogeneity and plasticity of hepatocyte lineage cells. | 2001 Mar |
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The preparation of anthraquinone used in the National Toxicology Program cancer bioassay was contaminated with the mutagen 9-nitroanthracene. | 2001 Mar |
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Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes. | 2001 Mar |
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Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population. | 2001 Mar 20 |
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Gas chromatographic-mass spectrometric determination of hydrophilic compounds in environmental water by solid-phase extraction with activated carbon fiber felt. | 2001 Mar 9 |
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Effect of cadmium and zinc-metallothionein on methemoglobin and nitric oxide in dimethylnitrosamine treated rats. | 2001 May |
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DNA damage induced by red food dyes orally administered to pregnant and male mice. | 2001 May |
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Induction of cytochrome P450-dependent monooxygenase in mouse liver and kidney by rutaecarpine, an alkaloid of the herbal drug Evodia rutaecarpa. | 2001 Nov 30 |
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TAC-101, a novel retinobenzoic-acid derivative, enhances gap junctional intercellular communication among renal epithelial cells treated with renal carcinogens. | 2001 Nov-Dec |
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Esophageal cancer prevention in zinc-deficient rats: rapid induction of apoptosis by replenishing zinc. | 2001 Oct 17 |
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N-nitrososdimethylamine is activated in microsomes from hepatocytes to reactive metabolites which damage DNA of non-parenchymal cells in rat liver. | 2001 Sep 15 |
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Determination of N-nitrosodimethylamine in environmental aqueous samples by isotope-dilution GC/MS-SIM. | 2001 Sep-Oct |
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Fast microwave-assisted dansylation of N-nitrosamines. Analysis by high-performance liquid chromatography with fluorescence detection. | 2002 Feb 8 |
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Effects of Wu-chu-yu-tang and its component herbs on drug-metabolizing enzymes. | 2002 Jul |
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Transgenic rats carrying human c-Ha-ras proto-oncogene are highly susceptible to N-nitrosomethylbenzylamine induction of esophageal tumorigenesis. | 2002 Jul |
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Volatile N-nitrosamine inhibition after intake Korean green tea and Maesil (Prunus mume SIEB. et ZACC.) extracts with an amine-rich diet in subjects ingesting nitrate. | 2002 Jul |
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Rapid in vivo assay for topical oral cancer chemopreventive agents. | 2002 Jul |
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Evidence for the presence of active cytochrome P450 systems in Schistosoma mansoni and Schistosoma haematobium adult worms. | 2002 May 22 |
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Cytochrome P450 2E1 dependent catalytic activity and lipid peroxidation in rat blood lymphocytes. | 2002 Oct 11 |
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Weak enhancing effects of simultaneous ethanol administration on chemically induced rat esophageal tumorigenesis. | 2002 Sep-Oct |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Jul 05 22:33:42 UTC 2023
by
admin
on
Wed Jul 05 22:33:42 UTC 2023
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Record UNII |
M43H21IO8R
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Record Status |
Validated (UNII)
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Record Version |
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Classification Tree | Code System | Code | ||
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IARC | <i>N</i>-Nitrosodimethylamine | ||
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NCI_THESAURUS |
C45398
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M7994
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59990
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N-NITROSODIMETHYLAMINE
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1466674
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C44417
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62-75-9
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Related Record | Type | Details | ||
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PARENT -> IMPURITY |
NDMA is an organic chemical that is in a family of potent carcinogens.
|
||
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PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is in a family of potent carcinogens.
|
||
|
PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is in a family of potent carcinogens.
|
||
|
PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is in a family of potent carcinogens.
|
||
|
PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is in a family of potent carcinogens.
|
||
|
PARENT -> IMPURITY |
NDMA is an organic chemical that is in a family of potent carcinogens.
|
||
|
PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is part of a family of potent carcinogens.
|
||
|
PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is in a family of potent carcinogens.
|
||
|
PARENT->IMPURITY GENOTOXIC |
NDMA is an organic chemical that is in a family of potent carcinogens.
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