PRAMIVERINE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H27N
Molecular Weight	293.4458
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)NC1CCC(CC1)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=SBEOBYJLAQKTQX-UHFFFAOYSA-N

InChI=1S/C21H27N/c1-17(2)22-20-13-15-21(16-14-20,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,17,20,22H,13-16H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C21H27N
Molecular Weight	293.4458
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/537712 | https://www.ncbi.nlm.nih.gov/pubmed/782470

Spasmolytic drug pramiverine was used in the active treatment of labor. In addition, it participated in clinical trials for patients with colitis syndrome. It was revealed, that pramiverine had improved the conditions of patients.

Approval Year

PubMed

Title	Date	PubMed
Effects of the spasmolytic and anticholinergic N-isopropyl-4,4-diphenylcyclohexylamine--HCl (HSp 2986) on experimental ulcer in rats.	1972 Jun	5068362
[Eosphagomanometric finding in man after intravenous administration of a new cholinolytic (pramiverine), atropine and scopolamine butylbromide].	1976 Apr	989022
[Organ distribution of 14C-pramiverine in the rat].	1976 Apr	989020
[Toxicological study on pramiverine (author's transl)].	1976 Apr	989019
[Experimental studies on pramiverine (author's transl)].	1976 Apr	989018
[On the cholinolytic activity of pramiverine].	1976 Apr	821493
[Therapeutic results with the combination pramiverine/metamizole in a multicentre trial (author's transl)].	1976 Apr	782472
[Pramiverine/metamizole - a spasmoanalgesic for routine therapy of symptoms in emergency/a clinical trial in patients with biliary colics (author's transl)].	1976 Apr	782471
[Clinical trial of a novel spasmolytic, pramiverine, and its influence in colitis (author's transl].	1976 Apr	782470
[Profile comment on clinical and experimental studies of pramiverine and pramiverine/metamizole (author's transl)].	1976 Apr	782469

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:33:36 GMT 2023` Edited by `admin` on `Fri Dec 15 15:33:36 GMT 2023`
Record UNII	157NY06G9T
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PRAMIVERINE

Official Name

English

SISTALGINA

Brand Name

English

EMD-9806

Code

English

HSP-2986

Code

English

HSP 2986

Code

English

pramiverine [INN]

Common Name

English

PRAMIVERIN [MI]

Common Name

English

Pramiverine [WHO-DD]

Common Name

English

EMD 9806

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29698