PRAMIVERINE HYDROCHLORIDE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H27N.ClH
Molecular Weight	329.907
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CC(C)NC1CCC(CC1)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=BMBNXHMQMNPCIV-UHFFFAOYSA-N

InChI=1S/C21H27N.ClH/c1-17(2)22-20-13-15-21(16-14-20,18-9-5-3-6-10-18)19-11-7-4-8-12-19;/h3-12,17,20,22H,13-16H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C21H27N
Molecular Weight	293.4458
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/537712 | https://www.ncbi.nlm.nih.gov/pubmed/782470

Spasmolytic drug pramiverine was used in the active treatment of labor. In addition, it participated in clinical trials for patients with colitis syndrome. It was revealed, that pramiverine had improved the conditions of patients.

Approval Year

PubMed

Title	Date	PubMed
[The effect of the combination pramiverine/metamizole in colic pain (author's transl)].	1976-04	989023
[Eosphagomanometric finding in man after intravenous administration of a new cholinolytic (pramiverine), atropine and scopolamine butylbromide].	1976-04	989022
[Gaschromatographic determination of pramiverine in body fluids (author's transl)].	1976-04	989021
[Organ distribution of 14C-pramiverine in the rat].	1976-04	989020
Toxicological study on pramiverine (author's transl).	1976-04	989019
[Experimental studies on pramiverine (author's transl)].	1976-04	989018
[Animal experimental study on spasmolytic and analgesic activities of pramiverine, metamizole and their combination (author's transl)].	1976-04	989017
[Metabolism of pramiverine (author's transl)].	1976-04	821495
[Pharmacokinetics of pramiverine in rats, dogs, and monkeys (author's transl)].	1976-04	821494
[On the cholinolytic activity of pramiverine].	1976-04	821493
[Therapeutic results with the combination pramiverine/metamizole in a multicentre trial (author's transl)].	1976-04	782472
[Pramiverine/metamizole - a spasmoanalgesic for routine therapy of symptoms in emergency/a clinical trial in patients with biliary colics (author's transl)].	1976-04	782471
[Clinical trial of a novel spasmolytic, pramiverine, and its influence in colitis (author's transl].	1976-04	782470
[Profile comment on clinical and experimental studies of pramiverine and pramiverine/metamizole (author's transl)].	1976-04	782469
Effects of the spasmolytic and anticholinergic N-isopropyl-4,4-diphenylcyclohexylamine--HCl (HSp 2986) on experimental ulcer in rats.	1972-06	5068362

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:19:34 GMT 2025` Edited by `admin` on `Mon Mar 31 19:19:34 GMT 2025`
Record UNII	X23ET5815S
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PRAMIVERIN HYDROCHLORIDE

Preferred Name

English

PRAMIVERINE HYDROCHLORIDE

Common Name

English

4,4-DIPHENYLCYCLOHEXYL(ISOPROPYL)AMMONIUM CHLORIDE

Systematic Name

English

(4,4-DIPHENYLCYCLOHEXYL)-ISOPROPYL-AMINE HYDROCHLORIDE

Systematic Name

English

PRAMIVERIN HYDROCHLORIDE [MI]

Common Name

English

Pramiverine hydrochloride [WHO-DD]

Common Name

English

Code System Code Type Description

PUBCHEM

197926