Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C8H15NO3 |
| Molecular Weight | 173.2096 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1(C)CO[C@@H](CC(O)=O)CN1
InChI
InChIKey=SEYCKMQSPUVYEF-LURJTMIESA-N
InChI=1S/C8H15NO3/c1-8(2)5-12-6(4-9-8)3-7(10)11/h6,9H,3-5H2,1-2H3,(H,10,11)/t6-/m0/s1
| Molecular Formula | C8H15NO3 |
| Molecular Weight | 173.2096 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Gamma-aminobutyric acidB (GABAB)-receptor mediation of different in vivo effects of gamma-butyrolactone. | 2008-02 |
|
| Effects of GABA(B) receptor antagonist, agonists and allosteric positive modulator on the cocaine-induced self-administration and drug discrimination. | 2007-11-28 |
|
| Effects of GABA(B) receptor agents on cocaine priming, discrete contextual cue and food induced relapses. | 2007-10-01 |
|
| Resuscitative treatments on 1,4-butanediol mortality in mice. | 2006-02 |
|
| Up-regulation of GABA(B) receptors by chronic administration of the GABA(B) receptor antagonist SCH 50,911. | 2005-05-16 |
|
| Gamma-hydroxybutyric acid (GHB) and the mesoaccumbens reward circuit: evidence for GABA(B) receptor-mediated effects. | 2005 |
|
| Protection by the GABAB receptor antagonist, SCH 50911, of gamma-hydroxybutyric acid-induced mortality in mice. | 2004-10-25 |
|
| 3-Morpholinylsydnonimine inhibits glutamatergic transmission in rat rostral ventrolateral medulla via peroxynitrite formation and adenosine release. | 2004-09 |
|
| Pharmacological characterisation of a cell line expressing GABA B1b and GABA B2 receptor subunits. | 2003-04-01 |
|
| Proconvulsive effect of the GABA(B) receptor antagonist, SCH 50911, in rats undergoing ethanol withdrawal syndrome. | 2002-06-12 |
|
| Central effects of 1,4-butanediol are mediated by GABA(B) receptors via its conversion into gamma-hydroxybutyric acid. | 2002-04-26 |
|
| GABA(B) receptor inhibition causes locomotor stimulation in mice. | 2001-12-14 |
|
| gamma-Hydroxybutyric acid and baclofen decrease extracellular acetylcholine levels in the hippocampus via GABA(B) receptors. | 2001-11-02 |
|
| Role of GABA(B) receptors in the sedative/hypnotic effect of gamma-hydroxybutyric acid. | 2001-10-12 |
|
| Modification of d-amphetamine-induced responses by baclofen in rats. | 2001-01 |
|
| The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen. | 2000-11 |
|
| Characterization of the antiabsence effects of SCH 50911, a GABA-B receptor antagonist, in the lethargic mouse, gamma-hydroxybutyrate, and pentylenetetrazole models. | 1995-09 |
|
| The pharmacology of SCH 50911: a novel, orally-active GABA-beta receptor antagonist. | 1995-09 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:08:25 GMT 2025
by
admin
on
Mon Mar 31 21:08:25 GMT 2025
|
| Record UNII |
13OB0KEU61
|
| Record Status |
Validated (UNII)
|
| Record Version |
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733717-87-8
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DTXSID701336120
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13OB0KEU61
Created by
admin on Mon Mar 31 21:08:25 GMT 2025 , Edited by admin on Mon Mar 31 21:08:25 GMT 2025
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| Related Record | Type | Details | ||
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TARGET -> INHIBITOR |
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SALT/SOLVATE -> PARENT |
