SCH-50911

Cl.CC1(C)CO[C@@H](CC(O)=O)CN1

InChIKey=QYYBBASPKHNBKA-RGMNGODLSA-N

InChI=1S/C8H15NO3.ClH/c1-8(2)5-12-6(4-9-8)3-7(10)11;/h6,9H,3-5H2,1-2H3,(H,10,11);1H/t6-;/m0./s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
GABA-B receptor 32 Target ID: CHEMBL2111463 Sources: https://www.sciencedirect.com/science/article/pii/S0960894X96002673	Antagonist 2778		1100.0 nM [IC50]

PubMed

Title	Date	PubMed
The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen.	2000 Nov	11082110
Gamma-hydroxybutyric acid (GHB) and the mesoaccumbens reward circuit: evidence for GABA(B) receptor-mediated effects.	2005	15708487
Up-regulation of GABA(B) receptors by chronic administration of the GABA(B) receptor antagonist SCH 50,911.	2005 May 16	15893746

Substance Class	Chemical Created by `admin` on `Sat Dec 16 02:02:49 GMT 2023` Edited by `admin` on `Sat Dec 16 02:02:49 GMT 2023`
Record UNII	Q5MMG73452
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

SCH-50911

Common Name

English

SCH 50911

Code

English

2-MORPHOLINEACETIC ACID, 5,5-DIMETHYL-, HYDROCHLORIDE (1:1), (2S)-

Common Name

English

2-MORPHOLINEACETIC ACID, 5,5-DIMETHYL-, HYDROCHLORIDE, (2S)-

Common Name

English

Code System Code Type Description

PUBCHEM

10130513