Floretyrosine F18

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C11H14FNO3
Molecular Weight	226.2347
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N[C@@H](CC1=CC=C(OCC[18F])C=C1)C(O)=O

InChI

InChIKey=QZZYPHBVOQMBAT-LRAGLOQXSA-N

InChI=1S/C11H14FNO3/c12-5-6-16-9-3-1-8(2-4-9)7-10(13)11(14)15/h1-4,10H,5-7,13H2,(H,14,15)/t10-/m0/s1/i12-1

HIDE SMILES / InChI

Molecular Formula	C11H14FNO3
Molecular Weight	226.2347
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/books/NBK23454/ | https://www.ncbi.nlm.nih.gov/pubmed/29173147

18F-FET (18F-Fluoroethyl-L-tyrosine) is a radiolabelled amino acid. It penetrates the blood-brain barrier by a specific amino acid transport system. In the brain, it is taken up into upregulated tumoral cells but not incorporated into proteins. It is used as a biomarker for positron emission tomography for imaging brain tumors, where it has higher specificity than 18F-FDG.

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:49:12 UTC 2023` Edited by `admin` on `Sat Dec 16 01:49:12 UTC 2023`
Record UNII	1326R5J1IA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Floretyrosine F18

Official Name

English

J1.857.391A

Code

English

FLUOROETHYL-L-TYROSINE (18F)

Common Name

English

Fluoroethyl-L-tyrosine (18F) [WHO-DD]

Common Name

English

FET F-18

Common Name

English

FLORETYROSINE F18 [USAN]

Common Name

English

18F-FET

Common Name

English

O-[2-(fluoro-<sup>18</sup>F)ethyl]-L-Tyrosine

Systematic Name

English

FLUOROETHYLTYROSINE F-18

Common Name

English

L-Tyrosine, O-[2-(fluoro-<sup>18</sup>F)ethyl]-

Systematic Name

English

2-FLUOROETHYLTYROSINE F-18

Common Name

English

Classification Tree Code System Code

WHO-ATC

V09IX10