U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C14H20FNO2S
Molecular Weight 285.378
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ORDOPIDINE

SMILES

CCN1CCC(CC1)C2=C(F)C(=CC=C2)S(C)(=O)=O

InChI

InChIKey=UKUPJASJNQDHPH-UHFFFAOYSA-N
InChI=1S/C14H20FNO2S/c1-3-16-9-7-11(8-10-16)12-5-4-6-13(14(12)15)19(2,17)18/h4-6,11H,3,7-10H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C14H20FNO2S
Molecular Weight 285.378
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Ordopidine (also known as ACR-325) is a dopaminergic stabilizer that acts as dopamine D2 receptor antagonists with low affinity. Ordopidine under the development of NeuroSearch participated in phase I trials for the treatment of Parkinson's disease and bipolar disorder. Information about the current study of this drug is not available.

Originator

Approval Year

Sample Use Guides

In Vivo Use Guide
Capsules, dose titration from 25 mg to 75 mg bid or matching placebo. Duration of dosing: 3 weeks
Route of Administration: Oral
Substance Class Chemical
Record UNII
0P43SIA7J6
Record Status Validated (UNII)
Record Version