CINEPAZET

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H28N2O6
Molecular Weight	392.4461
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of CINEPAZET

Structure Search

SMILES

CCOC(=O)CN1CCN(CC1)C(=O)\C=C\C2=CC(OC)=C(OC)C(OC)=C2

InChI

InChIKey=XDUOTWNXVDBCDY-VOTSOKGWSA-N

InChI=1S/C20H28N2O6/c1-5-28-19(24)14-21-8-10-22(11-9-21)18(23)7-6-15-12-16(25-2)20(27-4)17(13-15)26-3/h6-7,12-13H,5,8-11,14H2,1-4H3/b7-6+

HIDE SMILES / InChI

Molecular Formula	C20H28N2O6
Molecular Weight	392.4461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=_J2ti4EkYpkC&pg=PA1024&lpg=PA1024 | https://www.sciencedirect.com/science/article/pii/S0065774308612907

Cinepazet is an ethyl ester of cinepazic acid. It acts by inhibiting the influx of extracellular calcium into cells through the slow calcium channel in the cell membrane. In the 1970s cinepazet was marketed in France and Italy under tradename Vascoril for the treatment of angina.

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Voltage-gated L-type calcium channel 92 Target ID: CHEMBL2095229 Sources: https://www.sciencedirect.com/science/article/pii/S0065774308612907	Blocker 537

Patents

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:09:18 GMT 2023` Edited by `admin` on `Fri Dec 15 16:09:18 GMT 2023`
Record UNII	0LC95WWE9Q
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CINEPAZET

Official Name

English

cinepazet [INN]

Common Name

English

CINEPAZET [MI]

Common Name

English

Cinepazet [WHO-DD]

Common Name

English

ETHYL 4-(3,4,5-TRIMETHOXYCINNAMOYL)-1-PIPERAZINEACETATE

Systematic Name

English

1-PIPERAZINEACETIC ACID, 4-(1-OXO-3-(3,4,5-TRIMETHOXYPHENYL)-2-PROPENYL)-, ETHYL ESTER

Common Name

English

Classification Tree Code System Code

WHO-ATC

C01DX14

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

WHO-VATC

QC01DX14

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

NCI_THESAURUS

C29707

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

Code System Code Type Description

MESH

C020997

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

PRIMARY

CAS

23887-41-4

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

PRIMARY

EPA CompTox

DTXSID20878521

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

PRIMARY

FDA UNII

0LC95WWE9Q

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

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WIKIPEDIA

Cinepazet

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

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MERCK INDEX

m1070

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

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Merck Index

INN

3677

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

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EVMPD

SUB06291MIG

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

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CAS

88053-11-6

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

ALTERNATIVE

NCI_THESAURUS

C87281

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

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ECHA (EC/EINECS)

245-927-3

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

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DRUG BANK

DB13342

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

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PUBCHEM

6434395

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

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SMS_ID

100000081062

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

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DRUG CENTRAL

650

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

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ChEMBL

CHEMBL2110784

Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023

PRIMARY

Related Record Type Details


					F02NGQ0DSF

CINEPAZET MALEATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					0LC95WWE9Q

CINEPAZET

ACTIVE MOIETY