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Details

Stereochemistry ACHIRAL
Molecular Formula C20H28N2O6.C4H4O4
Molecular Weight 508.5183
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of CINEPAZET MALEATE

SMILES

OC(=O)\C=C/C(O)=O.CCOC(=O)CN1CCN(CC1)C(=O)\C=C\C2=CC(OC)=C(OC)C(OC)=C2

InChI

InChIKey=URWISVHSKBDRKE-GVTSEVKNSA-N
InChI=1S/C20H28N2O6.C4H4O4/c1-5-28-19(24)14-21-8-10-22(11-9-21)18(23)7-6-15-12-16(25-2)20(27-4)17(13-15)26-3;5-3(6)1-2-4(7)8/h6-7,12-13H,5,8-11,14H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b7-6+;2-1-

HIDE SMILES / InChI

Molecular Formula C4H4O4
Molecular Weight 116.0722
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Molecular Formula C20H28N2O6
Molecular Weight 392.4461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Description

Cinepazet is an ethyl ester of cinepazic acid. It acts by inhibiting the influx of extracellular calcium into cells through the slow calcium channel in the cell membrane. In the 1970s cinepazet was marketed in France and Italy under tradename Vascoril for the treatment of angina.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Patents

Patents

Substance Class Chemical
Created
by admin
on Tue Oct 22 19:49:36 UTC 2019
Edited
by admin
on Tue Oct 22 19:49:36 UTC 2019
Record UNII
F02NGQ0DSF
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CINEPAZET MALEATE
MART.   MI   USAN   WHO-DD  
USAN  
Official Name English
CINEPAZET MALEATE [WHO-DD]
Common Name English
CINEPAZET MALEATE [USAN]
Common Name English
ETHYL 4-(3,4,5-TRIMETHOXYCINNAMOYL)-1-PIPERAZINEACETATE MALEATE (1:1)
Systematic Name English
CINEPAZET MALEATE [MART.]
Common Name English
CINEPAZET MALEATE [MI]
Common Name English
1-PIPERAZINEACETIC ACID, 4-(1-OXO-3-(3,4,5-TRIMETHOXYPHENYL)-2-PROPENYL)-, ETHYL ESTER, (Z)-2-BUTENEDIOATE (1:1)
Common Name English
Code System Code Type Description
MERCK INDEX
M1070
Created by admin on Tue Oct 22 19:49:37 UTC 2019 , Edited by admin on Tue Oct 22 19:49:37 UTC 2019
PRIMARY Merck Index
PUBCHEM
6434394
Created by admin on Tue Oct 22 19:49:37 UTC 2019 , Edited by admin on Tue Oct 22 19:49:37 UTC 2019
PRIMARY
ECHA (EC/EINECS)
256-709-2
Created by admin on Tue Oct 22 19:49:37 UTC 2019 , Edited by admin on Tue Oct 22 19:49:37 UTC 2019
PRIMARY
MESH
C020997
Created by admin on Tue Oct 22 19:49:37 UTC 2019 , Edited by admin on Tue Oct 22 19:49:37 UTC 2019
PRIMARY
CAS
50679-07-7
Created by admin on Tue Oct 22 19:49:37 UTC 2019 , Edited by admin on Tue Oct 22 19:49:37 UTC 2019
PRIMARY
ChEMBL
CHEMBL2110784
Created by admin on Tue Oct 22 19:49:37 UTC 2019 , Edited by admin on Tue Oct 22 19:49:37 UTC 2019
PRIMARY
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PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY